Abstract
Beta-thalassaemia is a congenital haemolytic anaemia characterized by partial (intermedia, TI) or complete (major, TM) deficiency in the production of β-globin chains. The primary aim of this study was to determine the prevalence of thromboembolic events in patients with β-thalassaemia. To achieve this, a multiple-choice questionnaire was sent to 56 tertiary referral centres in eight countries (Lebanon, Italy, Israel, Greece, Egypt, Jordan, Saudi Arabia and Iran), requesting specific information on patients who had experienced a thromboembolic event. The study demonstrated that thromboembolic events occurred in a clinically relevant proportion (1.65%) of 8,860 thalassaemia patients (TI - 24.7% orTM - 75.3%) from the Mediterranean and Iran. Thromboembolism occurred 4.38 times more frequently in TI thanTM (p
| Original language | English |
|---|---|
| Pages (from-to) | 488-491 |
| Number of pages | 4 |
| Journal | Thrombosis and Haemostasis |
| Volume | 96 |
| Issue number | 4 |
| DOIs | |
| Publication status | Published - Oct 2006 |
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Keywords
- Thalassaemia intermedia
- Thalassaemia major
- Thrombosis
ASJC Scopus subject areas
- Hematology
Cite this
Prevalence of thromboembolic events among 8,860 patients with thalassaemia major and intermedia in the Mediterranean area and Iran. / Taher, Ali; Isma'eel, Hussain; Mehio, Ghassan; Bignamini, Daniela; Kattamis, Antonis; Rachmilewitz, Eliezer A.; Cappellini, Maria Domencia.
In: Thrombosis and Haemostasis, Vol. 96, No. 4, 10.2006, p. 488-491.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Prevalence of thromboembolic events among 8,860 patients with thalassaemia major and intermedia in the Mediterranean area and Iran
AU - Taher, Ali
AU - Isma'eel, Hussain
AU - Mehio, Ghassan
AU - Bignamini, Daniela
AU - Kattamis, Antonis
AU - Rachmilewitz, Eliezer A.
AU - Cappellini, Maria Domencia
PY - 2006/10
Y1 - 2006/10
N2 - Beta-thalassaemia is a congenital haemolytic anaemia characterized by partial (intermedia, TI) or complete (major, TM) deficiency in the production of β-globin chains. The primary aim of this study was to determine the prevalence of thromboembolic events in patients with β-thalassaemia. To achieve this, a multiple-choice questionnaire was sent to 56 tertiary referral centres in eight countries (Lebanon, Italy, Israel, Greece, Egypt, Jordan, Saudi Arabia and Iran), requesting specific information on patients who had experienced a thromboembolic event. The study demonstrated that thromboembolic events occurred in a clinically relevant proportion (1.65%) of 8,860 thalassaemia patients (TI - 24.7% orTM - 75.3%) from the Mediterranean and Iran. Thromboembolism occurred 4.38 times more frequently in TI thanTM (p
AB - Beta-thalassaemia is a congenital haemolytic anaemia characterized by partial (intermedia, TI) or complete (major, TM) deficiency in the production of β-globin chains. The primary aim of this study was to determine the prevalence of thromboembolic events in patients with β-thalassaemia. To achieve this, a multiple-choice questionnaire was sent to 56 tertiary referral centres in eight countries (Lebanon, Italy, Israel, Greece, Egypt, Jordan, Saudi Arabia and Iran), requesting specific information on patients who had experienced a thromboembolic event. The study demonstrated that thromboembolic events occurred in a clinically relevant proportion (1.65%) of 8,860 thalassaemia patients (TI - 24.7% orTM - 75.3%) from the Mediterranean and Iran. Thromboembolism occurred 4.38 times more frequently in TI thanTM (p
KW - Thalassaemia intermedia
KW - Thalassaemia major
KW - Thrombosis
UR - http://www.scopus.com/inward/record.url?scp=33749872392&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=33749872392&partnerID=8YFLogxK
U2 - 10.1160/TH06-05-0267
DO - 10.1160/TH06-05-0267
M3 - Article
C2 - 17003927
AN - SCOPUS:33749872392
VL - 96
SP - 488
EP - 491
JO - Thrombosis and Haemostasis
JF - Thrombosis and Haemostasis
SN - 0340-6245
IS - 4
ER -