Preventing adverse obstetric outcomes in women with genetic thrombophilia

Elvira Grandone, Vincenzo Brancaccio, Donatella Colaizzo, Natale Sciannamé, Giuseppe Pavone, Giovanni Di Minno, Maurizio Margaglione

Research output: Contribution to journalArticle

Abstract

Objective: To improve fetomaternal outcomes in women with obstetric complications and inherited causes of thrombophilia. Design: Clinical trial. Setting: Thrombophilic women with previous unexplained adverse outcomes. Patient(s): Twenty-five women with previous severe obstetric complications were treated during and after pregnancy. Intervention(s): Low fixed dose of heparin or aspirin. Main Outcome Measure(s): Fetomaternal outcome. Result(s): Low fixed dose of heparin were administered to 24 pregnant women, aspirin to 7. Overall, among 31 treated pregnant women, 28 (90.3%) compared to 4 of 58 (6.9%) in previous pregnancies had a good obstetric outcome. Two fetal losses

Original languageEnglish
Pages (from-to)371-375
Number of pages5
JournalFertility and Sterility
Volume78
Issue number2
DOIs
Publication statusPublished - 2002

Fingerprint

Thrombophilia
Obstetrics
Aspirin
Heparin
Pregnant Women
Pregnancy
Outcome Assessment (Health Care)
Clinical Trials

Keywords

  • Pregnancy complications
  • Thrombophilia
  • Thromboprophylaxis

ASJC Scopus subject areas

  • Obstetrics and Gynaecology

Cite this

Preventing adverse obstetric outcomes in women with genetic thrombophilia. / Grandone, Elvira; Brancaccio, Vincenzo; Colaizzo, Donatella; Sciannamé, Natale; Pavone, Giuseppe; Di Minno, Giovanni; Margaglione, Maurizio.

In: Fertility and Sterility, Vol. 78, No. 2, 2002, p. 371-375.

Research output: Contribution to journalArticle

Grandone, E, Brancaccio, V, Colaizzo, D, Sciannamé, N, Pavone, G, Di Minno, G & Margaglione, M 2002, 'Preventing adverse obstetric outcomes in women with genetic thrombophilia', Fertility and Sterility, vol. 78, no. 2, pp. 371-375. https://doi.org/10.1016/S0015-0282(02)03222-3
Grandone, Elvira ; Brancaccio, Vincenzo ; Colaizzo, Donatella ; Sciannamé, Natale ; Pavone, Giuseppe ; Di Minno, Giovanni ; Margaglione, Maurizio. / Preventing adverse obstetric outcomes in women with genetic thrombophilia. In: Fertility and Sterility. 2002 ; Vol. 78, No. 2. pp. 371-375.
@article{cf9ff95cee9748e3867a85ccc5a3027e,
title = "Preventing adverse obstetric outcomes in women with genetic thrombophilia",
abstract = "Objective: To improve fetomaternal outcomes in women with obstetric complications and inherited causes of thrombophilia. Design: Clinical trial. Setting: Thrombophilic women with previous unexplained adverse outcomes. Patient(s): Twenty-five women with previous severe obstetric complications were treated during and after pregnancy. Intervention(s): Low fixed dose of heparin or aspirin. Main Outcome Measure(s): Fetomaternal outcome. Result(s): Low fixed dose of heparin were administered to 24 pregnant women, aspirin to 7. Overall, among 31 treated pregnant women, 28 (90.3{\%}) compared to 4 of 58 (6.9{\%}) in previous pregnancies had a good obstetric outcome. Two fetal losses",
keywords = "Pregnancy complications, Thrombophilia, Thromboprophylaxis",
author = "Elvira Grandone and Vincenzo Brancaccio and Donatella Colaizzo and Natale Sciannam{\'e} and Giuseppe Pavone and {Di Minno}, Giovanni and Maurizio Margaglione",
year = "2002",
doi = "10.1016/S0015-0282(02)03222-3",
language = "English",
volume = "78",
pages = "371--375",
journal = "Fertility and Sterility",
issn = "0015-0282",
publisher = "Elsevier Inc.",
number = "2",

}

TY - JOUR

T1 - Preventing adverse obstetric outcomes in women with genetic thrombophilia

AU - Grandone, Elvira

AU - Brancaccio, Vincenzo

AU - Colaizzo, Donatella

AU - Sciannamé, Natale

AU - Pavone, Giuseppe

AU - Di Minno, Giovanni

AU - Margaglione, Maurizio

PY - 2002

Y1 - 2002

N2 - Objective: To improve fetomaternal outcomes in women with obstetric complications and inherited causes of thrombophilia. Design: Clinical trial. Setting: Thrombophilic women with previous unexplained adverse outcomes. Patient(s): Twenty-five women with previous severe obstetric complications were treated during and after pregnancy. Intervention(s): Low fixed dose of heparin or aspirin. Main Outcome Measure(s): Fetomaternal outcome. Result(s): Low fixed dose of heparin were administered to 24 pregnant women, aspirin to 7. Overall, among 31 treated pregnant women, 28 (90.3%) compared to 4 of 58 (6.9%) in previous pregnancies had a good obstetric outcome. Two fetal losses

AB - Objective: To improve fetomaternal outcomes in women with obstetric complications and inherited causes of thrombophilia. Design: Clinical trial. Setting: Thrombophilic women with previous unexplained adverse outcomes. Patient(s): Twenty-five women with previous severe obstetric complications were treated during and after pregnancy. Intervention(s): Low fixed dose of heparin or aspirin. Main Outcome Measure(s): Fetomaternal outcome. Result(s): Low fixed dose of heparin were administered to 24 pregnant women, aspirin to 7. Overall, among 31 treated pregnant women, 28 (90.3%) compared to 4 of 58 (6.9%) in previous pregnancies had a good obstetric outcome. Two fetal losses

KW - Pregnancy complications

KW - Thrombophilia

KW - Thromboprophylaxis

UR - http://www.scopus.com/inward/record.url?scp=0036321722&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0036321722&partnerID=8YFLogxK

U2 - 10.1016/S0015-0282(02)03222-3

DO - 10.1016/S0015-0282(02)03222-3

M3 - Article

C2 - 12137876

AN - SCOPUS:0036321722

VL - 78

SP - 371

EP - 375

JO - Fertility and Sterility

JF - Fertility and Sterility

SN - 0015-0282

IS - 2

ER -