Prevention and control of type 2 diabetes by Mediterranean diet: A systematic review

Katherine Esposito, Maria Ida Maiorino, Antonio Ceriello, Dario Giugliano

Research output: Contribution to journalArticle

Abstract

We conducted a systematic review of the available studies that assessed the effect of a Mediterranean diet in type 2 diabetes. We searched publications up to 30 November 2009. Seventeen studies were included. Two large prospective studies report a substantially lower risk (83% and 35%, respectively) of type 2 diabetes in healthy people or in post-infarct patients with the highest adherence to a Mediterranean diet. Five randomized controlled trials have evaluated the effects of a Mediterranean diet, as compared with other commonly used diets, on indices of glycaemic control in subjects with type 2 diabetes. Improvement of fasting glucose and HbA1c levels was greater with a Mediterranean diet and ranged from 7 to 40. mg/dl for fasting glucose, and from 0.1 to 0.6% for HbA1c. No trial reported worsening of glycaemic control with a Mediterranean diet. Two controlled trials in a secondary prevention setting demonstrated that post-infarct patients, including diabetic patients, had cardiovascular benefits from a Mediterranean diet. The evidence so far accumulated suggests that adopting a Mediterranean diet may help prevent type 2 diabetes, and also improve glycaemic control and cardiovascular risk in persons with established diabetes.

Original languageEnglish
Pages (from-to)97-102
Number of pages6
JournalDiabetes Research and Clinical Practice
Volume89
Issue number2
DOIs
Publication statusPublished - Aug 2010

Keywords

  • Cardiovascular risk
  • Glycaemic control
  • Mediterranean diet
  • Prevention
  • Type 2 diabetes

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Internal Medicine
  • Endocrinology
  • Medicine(all)

Fingerprint Dive into the research topics of 'Prevention and control of type 2 diabetes by Mediterranean diet: A systematic review'. Together they form a unique fingerprint.

  • Cite this