Prevention and treatment of acute GvHD

C. Messina, M. Faraci, V. de Fazio, G. Dini, M. P. Calò, E. Calore

Research output: Contribution to journalArticlepeer-review

Abstract

GvHD remains a source of significant morbidity and mortality in the setting of allogeneic haematopoietic SCT. Improving outcomes in stem cell transplant recipients requires additional therapeutic modalities for GvHD, especially for patients who fail to respond to initial therapy with steroids. Moreover, while the absence of acute GvHD (aGvHD) is associated with a higher risk of relapse of the underlying malignant disease, severe aGvHD usually induces the occurrence of life-threatening complications such as severe infections. This article summarizes the current state of aGvHD prophylaxis and treatment.

Original languageEnglish
JournalBone Marrow Transplantation
Volume41
Issue numberSUPPL. 2
DOIs
Publication statusPublished - Jun 2008

ASJC Scopus subject areas

  • Hematology
  • Transplantation

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