Prevention and treatment of oral mucositis in patients with head and neck cancer treated with (chemo) radiation: Report of an Italian survey

Paolo Bossi, Gianmauro Numico, Vitaliana De Santis, Maria Grazia Ruo Redda, Alessia Reali, Liliana Belgioia, Maria Cossu Rocca, Ester Orlandi, Mario Airoldi, Alamalina Bacigalupo, Marta Mazzer, Gabriella Saibene, Elvio Russi

Research output: Contribution to journalArticlepeer-review

Abstract

Purpose: There is a limited number of therapies with a high level of recommendations for mucositis, while several strategies are currently employed with a limited evidence for efficacy. A national survey among Italian oncologists who treat head and neck cancer (HNC) was conducted in order to assess the most common preventive and therapeutic protocols (including nutritional support and pain control) for oral mucositis (OM) in patients undergoing chemoradiotherapy. Methods: From September to November 2012, a nationwide electronic survey with 21 focused items was proposed to chemotherapy and radiotherapy centers. Results: We collected 111 answers. Common Terminology Criteria for Adverse Events (CTCAE) scale is employed by 55 % of the physicians in assessing mucosal toxicity. The most relevant predictive factors for OM development are considered smoke, alcohol use, planned radiotherapy, and concurrent use of radiosensitizing chemotherapy. Prophylactic gastrostomy is adopted in

Original languageEnglish
Pages (from-to)1889-1896
Number of pages8
JournalSupportive Care in Cancer
Volume22
Issue number7
DOIs
Publication statusPublished - 2014

Keywords

  • Head and neck cancer
  • Oral mucositis
  • Prevention and treatment
  • Standard of care

ASJC Scopus subject areas

  • Oncology

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