TY - JOUR
T1 - Prevention of cardiovascular risk by moderate alcohol consumption
T2 - Epidemiologic evidence and plausible mechanisms
AU - Di Castelnuovo, Augusto
AU - Costanzo, Simona
AU - Donati, Maria Benedetta
AU - Iacoviello, Licia
AU - de Gaetano, Giovanni
PY - 2010
Y1 - 2010
N2 - An inverse association between moderate alcohol intake and cardiovascular risk, in particular coronary disease and ischemic stroke, has been shown in many epidemiologic studies. In addition, several other diseases are also known to occur less frequently in moderate drinkers than in non-drinkers, whereas excess of drinking is invariably harmful. However, some concern has been recently raised about the possibility that at all dosages the harm of alcohol could overcome its beneficial effects. We present here the epidemiologic and mechanistic evidence to support the protective effect of moderate alcohol intake against cardiovascular disease and all-cause mortality.
AB - An inverse association between moderate alcohol intake and cardiovascular risk, in particular coronary disease and ischemic stroke, has been shown in many epidemiologic studies. In addition, several other diseases are also known to occur less frequently in moderate drinkers than in non-drinkers, whereas excess of drinking is invariably harmful. However, some concern has been recently raised about the possibility that at all dosages the harm of alcohol could overcome its beneficial effects. We present here the epidemiologic and mechanistic evidence to support the protective effect of moderate alcohol intake against cardiovascular disease and all-cause mortality.
KW - Alcohol
KW - Total mortality
KW - Vascular risk
KW - Wine
UR - http://www.scopus.com/inward/record.url?scp=77955052915&partnerID=8YFLogxK
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U2 - 10.1007/s11739-010-0346-0
DO - 10.1007/s11739-010-0346-0
M3 - Article
C2 - 20127425
AN - SCOPUS:77955052915
VL - 5
SP - 291
EP - 297
JO - Internal and Emergency Medicine
JF - Internal and Emergency Medicine
SN - 1828-0447
IS - 4
ER -