82 patients treated with adriamycin alone or in combination with other cytostatic agents underwent scalp hypothermia by application of a gel cap. The cap was applied 10 minutes before the injection of the drugs and maintained until 30 minutes after the administration of the chemotherapy. Prevention of hair loss was achieved in 47 patients (57%). The prophylaxis was successful in 16 out of 21 males (76%) compared with 31 out of 61 female patients (p <0.05). No statistically significant difference was found between patients receiving higher or lower doses of adriamycin or between patients with or without liver dysfunction. The tolerance of the gel cap was excellent; only one patient did not tolerate the cap because of anxiety during application.
|Translated title of the contribution||Prevention of cytostatic drug-induced alopecia by scalp hypothermia with a gel cap|
|Number of pages||4|
|Journal||Schweizerische Medizinische Wochenschrift|
|Publication status||Published - 1982|
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