Prevention of functional gastrointestinal disorders in neonates: Clinical and socioeconomic impact

F. Indrio, A. Di Mauro, G. Riezzo, R. Panza, L. Cavallo, R. Francavilla

Research output: Contribution to journalArticle


Infantile colic, gastro-oesophageal reflux and constipation are the most common functional gastrointestinal disorders (FGIDs) affecting infants during the first months of life. Despite infantile colic, functional constipation and regurgitation had a self-limited pattern, they are considered a risk factor for developing different disorders later in life. The pathophysiology of these functional diseases is still controversial but there is growing evidence that an abnormal gut microbiota colonisation may play a crucial role. An early probiotic supplementation could determine a change in colonisation and may represent a new strategy for preventing FGIDs.

Original languageEnglish
Pages (from-to)195-198
Number of pages4
JournalBeneficial microbes
Issue number2
Publication statusPublished - 2015



  • FGIDs
  • Infants
  • Lactobacillus reuteri
  • Neonates
  • Probiotics

ASJC Scopus subject areas

  • Microbiology (medical)
  • Microbiology

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