Prevention of hemoperitoneum during ovulation by oral contraceptives in women with type III von Willebrand disease and afibrinogenemia. Case reports

E. Bottini, F. I. Pareti, D. Mari, P. M. Mannucci, M. L. Muggiasca, M. Conti

Research output: Contribution to journalArticlepeer-review

Abstract

The follicle ruptures at the time of ovulation and fills with blood, forming a corpus hemorrhagicum. Minor bleeding from the follicle into the abdominal cavity may cause peritoneal irritation and, when occurring in a patient with a defect of primary hemostasis, hemoperitoneum can occur. Von Willebrand disease and afibrinogenemia are 2 important bleeding disorders in which both primary hemostasis and coagulation are involved. Bleeding during ovulation is 1 major clinical complication in women with these diseases. The authors examined 3 patients with this hemorrhagic complication and data show that oral contraceptives are an effective means to avoid hemoperitoneum. author's modified

Original languageEnglish
Pages (from-to)431-433
Number of pages3
JournalHaematologica
Volume76
Issue number5
Publication statusPublished - 1991

ASJC Scopus subject areas

  • Hematology

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