Abstract
The efficacy of preventing ischemia-reperfusion damage by employing native or modified (mPEG-SOD) superoxide dismutase in an experimental model of acute ischemia was tested in the left hind limb of 43 Wistar rats. A significative difference (p=0.004) of the survival leg rate was found in the group treated with mPEG-SOD (86.6%) compared with the control group (30%). This difference was confirmed both clinically and by TEM analysis of muscular specimens.
| Original language | English |
|---|---|
| Pages (from-to) | 125-132 |
| Number of pages | 8 |
| Journal | Bollettino della Societa Italiana di Biologia Sperimentale |
| Volume | 71 |
| Issue number | 5-6 |
| Publication status | Published - May 1995 |
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Prevention of ischemia-reperfusion damage with polymerized superoxide dismutase. / Rocca, M.; Capelli, S.; Fini, M.; Maltarello, M. C.; Veronese, F. M.; Caliceti, P.; Giardino, R.
In: Bollettino della Societa Italiana di Biologia Sperimentale, Vol. 71, No. 5-6, 05.1995, p. 125-132.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Prevention of ischemia-reperfusion damage with polymerized superoxide dismutase.
AU - Rocca, M.
AU - Capelli, S.
AU - Fini, M.
AU - Maltarello, M. C.
AU - Veronese, F. M.
AU - Caliceti, P.
AU - Giardino, R.
PY - 1995/5
Y1 - 1995/5
N2 - The efficacy of preventing ischemia-reperfusion damage by employing native or modified (mPEG-SOD) superoxide dismutase in an experimental model of acute ischemia was tested in the left hind limb of 43 Wistar rats. A significative difference (p=0.004) of the survival leg rate was found in the group treated with mPEG-SOD (86.6%) compared with the control group (30%). This difference was confirmed both clinically and by TEM analysis of muscular specimens.
AB - The efficacy of preventing ischemia-reperfusion damage by employing native or modified (mPEG-SOD) superoxide dismutase in an experimental model of acute ischemia was tested in the left hind limb of 43 Wistar rats. A significative difference (p=0.004) of the survival leg rate was found in the group treated with mPEG-SOD (86.6%) compared with the control group (30%). This difference was confirmed both clinically and by TEM analysis of muscular specimens.
UR - http://www.scopus.com/inward/record.url?scp=0029295556&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0029295556&partnerID=8YFLogxK
M3 - Article
C2 - 8519486
AN - SCOPUS:0029295556
VL - 71
SP - 125
EP - 132
JO - Bollettino della Societa Italiana di Biologia Sperimentale
JF - Bollettino della Societa Italiana di Biologia Sperimentale
SN - 0037-8771
IS - 5-6
ER -