Abstract
The efficacy of preventing ischemia-reperfusion damage by employing native or modified (mPEG-SOD) superoxide dismutase in an experimental model of acute ischemia was tested in the left hind limb of 43 Wistar rats. A significative difference (p=0.004) of the survival leg rate was found in the group treated with mPEG-SOD (86.6%) compared with the control group (30%). This difference was confirmed both clinically and by TEM analysis of muscular specimens.
| Original language | English |
|---|---|
| Pages (from-to) | 125-132 |
| Number of pages | 8 |
| Journal | Bollettino della Societa Italiana di Biologia Sperimentale |
| Volume | 71 |
| Issue number | 5-6 |
| Publication status | Published - May 1995 |
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Cite this
Rocca, M., Capelli, S., Fini, M., Maltarello, M. C., Veronese, F. M., Caliceti, P., & Giardino, R. (1995). Prevention of ischemia-reperfusion damage with polymerized superoxide dismutase. Bollettino della Societa Italiana di Biologia Sperimentale, 71(5-6), 125-132.