Prevention of venous thrombosis with elastic stockings during long-haul flights: The LONFLIT 5 JAP study

G. Belcaro, M. R. Cesarone, A. N. Nicolaides, A. Ricci, G. Geroulakos, S. S G Shah, E. Ippolito, K. A. Myers, P. Bavera, M. Dugall, M. Moia, A. Di Renzo, B. M. Errichi, R. Brandolini, M. Griffin, I. Ruffini, G. Acerbi

Research output: Contribution to journalArticle

Abstract

The aim of this study was to evaluate deep venous thrombosis (DVT) prophylaxis with specific elastic stockings in long-haul flights (11-13 hours), in high-risk subjects. A group of 300 subjects was included; 76 were excluded for several problems including concomitant treatments; 224 were randomized into two groups (stockings vs. controls) to evaluate prophylaxis with below-knee stockings. An exercise program was used in both groups. Scholl (UK) Flight Socks (14-17 mmHg of pressure at the ankle) were used. DVT was diagnosed with ultrasound scanning. The femoral, popliteal, and tibial veins were scanned before and within 90 minutes after the flights. Of the 205 included subjects, 102 controls and 103 treated subjects completed the study. Drop-outs were due to flight connection problems. Age, gender, and risk distributions were comparable in the two groups. In the treatment group (103 subjects; mean age, 42; SD 9; M:F, 55:48), one limited, distal DVT was observed (0.97%). In the control group (102 subjects; mean age, 42.1; SD 10.3; M:F, 56:46), six subjects (5.8%) had a DVT. There were no superficial thromboses. The difference in DVT incidence is significant (p

Original languageEnglish
Pages (from-to)197-201
Number of pages5
JournalClinical and Applied Thrombosis/Hemostasis
Volume9
Issue number3
Publication statusPublished - Jul 2003

Keywords

  • Airplanes
  • Deep venous thrombosis
  • Edema
  • Elastic compression
  • Flight-microangiopathy
  • Long-haul flights
  • Noninvasive investigations
  • Prevention
  • Travel
  • Ultrasound

ASJC Scopus subject areas

  • Hematology

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  • Cite this

    Belcaro, G., Cesarone, M. R., Nicolaides, A. N., Ricci, A., Geroulakos, G., Shah, S. S. G., Ippolito, E., Myers, K. A., Bavera, P., Dugall, M., Moia, M., Di Renzo, A., Errichi, B. M., Brandolini, R., Griffin, M., Ruffini, I., & Acerbi, G. (2003). Prevention of venous thrombosis with elastic stockings during long-haul flights: The LONFLIT 5 JAP study. Clinical and Applied Thrombosis/Hemostasis, 9(3), 197-201.