Primary breast leiomyosarcoma and synchronous homolateral lung cancer: a case report

Alberto Testori, Stefano Meroni, Emanuele Voulaz, Marco Alloisio, Rita De Sanctis, Paola Bossi, Umberto Cariboni, Matilde De Simone, Ugo Cioffi

Research output: Contribution to journalArticlepeer-review


Radiological and histological features of breast leiomyosarcoma can mimic a wide variety of other breast lesions, such as mesenchymal tumors, breast lymphomas, poorly differentiated carcinomas and metaplastic breast carcinomas. The authors present the case of a 62-year-old woman with a primary breast leiomyosarcoma with synchronous ipsilateral lung adenocarcinoma. The latter was an incidental finding during pre-surgical staging examinations. Clinicopathological, immunophenotypic and imaging features cancer are described. A brief review of the literature on imaging findings and management of breast leiomyosarcoma is presented. The authors discuss the differential diagnoses in breast imaging and of the extra-mammary incidental findings. Surgical resection remains the cornerstone of treatment, while radiation therapy and chemotherapy remain to be defined on a single-patient basis.
Original languageEnglish
Pages (from-to)E1054-E1059
JournalJournal of Thoracic Disease
Issue number12
Publication statusPublished - Dec 1 2017


  • Breast leiomyosarcoma
  • Lung cancer
  • Synchronous tumors


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