TY - JOUR
T1 - Primary cervical melanoma with brain metastases. Case report and review of the literature
AU - Salpietro, Francesco M.
AU - Alafaci, Concetta
AU - Gervasio, Olga
AU - La Rosa, Giovanni
AU - Baio, Ambrogia
AU - Francolini, Dario Cavallini
AU - Batolo, Dario
AU - Tomasello, Francesco
PY - 1998/10
Y1 - 1998/10
N2 - Primary intramedullary melanoma is a very rare tumor that occurs most frequently in the middle or lower thoracic spinal cord. The authors present a case of primary cervical cord melanoma that developed in a 62-year-old man who was surgically treated and subsequently underwent radiation therapy. Clinical and histogenetic features of this neoplasm and results of chemo-, radio-, and immunotherapy are reported. Both 'dysembryogenetic' and 'mesodermal' hypotheses on the origin of primary spinal melanoma are discussed.
AB - Primary intramedullary melanoma is a very rare tumor that occurs most frequently in the middle or lower thoracic spinal cord. The authors present a case of primary cervical cord melanoma that developed in a 62-year-old man who was surgically treated and subsequently underwent radiation therapy. Clinical and histogenetic features of this neoplasm and results of chemo-, radio-, and immunotherapy are reported. Both 'dysembryogenetic' and 'mesodermal' hypotheses on the origin of primary spinal melanoma are discussed.
KW - Intramedullary lesion
KW - Melanoma
KW - Spinal cord tumor
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M3 - Article
C2 - 9761064
AN - SCOPUS:0031660976
VL - 89
SP - 659
EP - 666
JO - Journal of Neurosurgery
JF - Journal of Neurosurgery
SN - 0022-3085
IS - 4
ER -