Primary CNS demyelinating diseases in childhood: Multiple sclerosis

P. Iannetti, M. G. Marciani, A. Spalice, F. Spanedda, U. Raucci, G. Trasimeni, G. F. Gualdi, G. Bernardi

Research output: Contribution to journalArticle

Abstract

We report on five children (three female and two male, age span 11-16 years) with laboratory supported definite multiple sclerosis or clinically definite multiple sclerosis, diagnosed on the basis of Poser and Paty criteria. All patients were subjected to serial clinical examinations, magnetic resonance investigations, CSF biochemical and immunological studies, and neurophysiological and neuropsychological assessments. Four of the five examined subjects underwent steroid treatment. Over a period of 3 years relapses have been observed in three of them. The first symptoms and signs of multiple sclerosis may be subtle and misleading; careful assessment of them may be crucial for an early diagnosis of the disease.

Original languageEnglish
Pages (from-to)149-154
Number of pages6
JournalChild's Nervous System
Volume12
Issue number3
DOIs
Publication statusPublished - Mar 1996

Fingerprint

Central Nervous System Diseases
Demyelinating Diseases
Multiple Sclerosis
Signs and Symptoms
Early Diagnosis
Magnetic Resonance Spectroscopy
Steroids
Recurrence
Therapeutics

Keywords

  • Childhood
  • Demyelinating diseases
  • Multiple sclerosis

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Clinical Neurology

Cite this

Iannetti, P., Marciani, M. G., Spalice, A., Spanedda, F., Raucci, U., Trasimeni, G., ... Bernardi, G. (1996). Primary CNS demyelinating diseases in childhood: Multiple sclerosis. Child's Nervous System, 12(3), 149-154. https://doi.org/10.1007/BF00266819

Primary CNS demyelinating diseases in childhood : Multiple sclerosis. / Iannetti, P.; Marciani, M. G.; Spalice, A.; Spanedda, F.; Raucci, U.; Trasimeni, G.; Gualdi, G. F.; Bernardi, G.

In: Child's Nervous System, Vol. 12, No. 3, 03.1996, p. 149-154.

Research output: Contribution to journalArticle

Iannetti, P, Marciani, MG, Spalice, A, Spanedda, F, Raucci, U, Trasimeni, G, Gualdi, GF & Bernardi, G 1996, 'Primary CNS demyelinating diseases in childhood: Multiple sclerosis', Child's Nervous System, vol. 12, no. 3, pp. 149-154. https://doi.org/10.1007/BF00266819
Iannetti P, Marciani MG, Spalice A, Spanedda F, Raucci U, Trasimeni G et al. Primary CNS demyelinating diseases in childhood: Multiple sclerosis. Child's Nervous System. 1996 Mar;12(3):149-154. https://doi.org/10.1007/BF00266819
Iannetti, P. ; Marciani, M. G. ; Spalice, A. ; Spanedda, F. ; Raucci, U. ; Trasimeni, G. ; Gualdi, G. F. ; Bernardi, G. / Primary CNS demyelinating diseases in childhood : Multiple sclerosis. In: Child's Nervous System. 1996 ; Vol. 12, No. 3. pp. 149-154.
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