Primary cutaneous and subcutaneous Ewing sarcoma

Angela Di Giannatale, Anna Maria Frezza, Marie Cécile Le Deley, Perrine Marec-Bérard, Charlotte Benson, Jean Yves Blay, Binh Bui, Ian Judson, Odile Oberlin, Jeremy Whelan, Nathalie Gaspar

Research output: Contribution to journalArticle

Abstract

Background: Primary cutaneous/subcutaneous Ewing sarcoma (scEWS) is extremely rare. We describe clinical features, treatment, and outcome of this Ewing localization. Procedure: Retrospective study (1996-2012) on 56 patients. Results: Most primary scEWS occurred in late adolescent/young adult females (F/M=1.9; median age 21.5 years), with primary tumor in the extremity/trunk (48.5%/39%). Only 35/56 samples had Real-Time-Polymerase-Chain-Reaction/Fluorescent-In-Situ-Hybridization analysis, 32/35 had EWS-translocation. Most of them exhibited known favorable prognostic factors: localized disease (54/56), initial tumor volume

Original languageEnglish
Pages (from-to)1555-1561
Number of pages7
JournalPediatric Blood and Cancer
Volume62
Issue number9
DOIs
Publication statusPublished - Sep 1 2015

Keywords

  • Adolescent
  • Cutaneous
  • Ewing sarcoma
  • Subcutaneous
  • Young adults

ASJC Scopus subject areas

  • Oncology
  • Pediatrics, Perinatology, and Child Health
  • Hematology
  • Medicine(all)

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  • Cite this

    Di Giannatale, A., Frezza, A. M., Le Deley, M. C., Marec-Bérard, P., Benson, C., Blay, J. Y., Bui, B., Judson, I., Oberlin, O., Whelan, J., & Gaspar, N. (2015). Primary cutaneous and subcutaneous Ewing sarcoma. Pediatric Blood and Cancer, 62(9), 1555-1561. https://doi.org/10.1002/pbc.25535