Primary diffuse meningeal melanomatosis: Radiologic-pathologic correlation

Maria Giulia Pirini; Mario Mascalchi; Fabrizio Salvi; Carlo A. Tassinari; Licciana Zanella; Patrizia Bacchini; Franco Bertoni; Antonia D'Errico; Barbara Corti; Walter F. Grigioni

Primary diffuse meningeal melanomatosis: Radiologic-pathologic correlation

Maria Giulia Pirini, Mario Mascalchi, Fabrizio Salvi, Carlo A. Tassinari, Licciana Zanella, Patrizia Bacchini, Franco Bertoni, Antonia D'Errico, Barbara Corti, Walter F. Grigioni

Istituto Scienze Neurologiche

Research output: Contribution to journal › Article › peer-review

Abstract

We report a case of primary diffuse meningeal melanomatosis, a rare variant of primary malignant melanoma of the CNS, in a 68-year-old woman. The disease mimicked intracranial hypotension syndrome and was diagnosed only at autopsy (CSF cytologic results were negative). CT revealed hydrocephalus with effacement of the cerebral convexity sulci and abnormal contrast enhancement in the right sylvian and frontoparietal fissures, whereas MR imaging showed diffuse marked dural and leptomeningeal contrast enhancement. In retrospect, these nonspecific findings correlated with the extensive leptomeningeal invasion in the cerebral hemispheres, brain stem and spinal cord. The clinical, radiologic, and pathologic features of diffuse meningeal melanomatosis are reviewed.

Original language	English
Pages (from-to)	115-118
Number of pages	4
Journal	American Journal of Neuroradiology
Volume	24
Issue number	1
Publication status	Published - Jan 2003

ASJC Scopus subject areas

Clinical Neurology
Radiology Nuclear Medicine and imaging
Radiological and Ultrasound Technology

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Primary diffuse meningeal melanomatosis : Radiologic-pathologic correlation. / Pirini, Maria Giulia; Mascalchi, Mario; Salvi, Fabrizio; Tassinari, Carlo A.; Zanella, Licciana; Bacchini, Patrizia; Bertoni, Franco; D'Errico, Antonia; Corti, Barbara; Grigioni, Walter F.

In: American Journal of Neuroradiology, Vol. 24, No. 1, 01.2003, p. 115-118.

Research output: Contribution to journal › Article › peer-review

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AU - Zanella, Licciana

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