Iperparatiroidismo primitivo. Analisi critica di un'esperienza di 20 anni

Translated title of the contribution: Primary hyperparathyroidism. A 20-year experience and a critical review

G. Favia, F. Lumachi, F. Reale, A. Sommariva, D. F. D'Amico

Research output: Contribution to journalArticle

Abstract

Purpose. The aim of this study was to review our 20-year experience in the treatment of primary hyperparathyroidism (HPT) and to analyze clinical and biochemical findings in patients surgically treated in the nineties and before. Material and methods. From 1978 to 1997, 302 patients with proved HPT underwent primary surgery. There were 95 (31.5%) males and 207 (68.5%) females with a median age of 53 years (range 11-82 years). Two groups of patients were considered: Group 1 (156 patients undergoing surgery between 1978 and 1989) and Group 2 (146 patients undergoing surgery from 1990 to 1997). Results. No differences (p = NS) were found regarding age at operation and preoperative serum creatinine values: The most frequent symptoms in both groups were of reumatho-logical nature (54.5% and 42.5% in Groups 1 and 2 respectively). Renal stones were described in 60.3% and 42.5% of Group 1 and 2 patients, while peptic ulcerations or gastritis were present in 25.0% and 15.1%. No differences (p = NS) in the number of patients with neurological and neuropsychiatry rate and in the median size of the removed parathyroid glands were observed between the two groups. Asymptomatic HPT was more frequent (20.5% vs 7.7%) in patients who underwent parathyroidectomy from 1990. Average serum calcium preoperative levels arid delayed diagnosis were greater (p <0.01) in Group 1 (3.10 vs 2.90 mmol/L and 72 vs 24 months respectively). Conclusion. Increase of asymptomatic patients with HPT allowing an earlier surgical treatment may reduce the time of the of neck exploration and morbidity rate.

Original languageItalian
Pages (from-to)399-403
Number of pages5
JournalAnnali Italiani di Chirurgia
Volume70
Issue number3
Publication statusPublished - May 1999

Fingerprint

Primary Hyperparathyroidism
Hyperparathyroidism
Neuropsychiatry
Parathyroidectomy
Parathyroid Glands
Delayed Diagnosis
Gastritis
Serum
Digestion
Creatinine
Neck
Calcium
Morbidity
Kidney
Therapeutics

ASJC Scopus subject areas

  • Surgery

Cite this

Favia, G., Lumachi, F., Reale, F., Sommariva, A., & D'Amico, D. F. (1999). Iperparatiroidismo primitivo. Analisi critica di un'esperienza di 20 anni. Annali Italiani di Chirurgia, 70(3), 399-403.

Iperparatiroidismo primitivo. Analisi critica di un'esperienza di 20 anni. / Favia, G.; Lumachi, F.; Reale, F.; Sommariva, A.; D'Amico, D. F.

In: Annali Italiani di Chirurgia, Vol. 70, No. 3, 05.1999, p. 399-403.

Research output: Contribution to journalArticle

Favia, G, Lumachi, F, Reale, F, Sommariva, A & D'Amico, DF 1999, 'Iperparatiroidismo primitivo. Analisi critica di un'esperienza di 20 anni', Annali Italiani di Chirurgia, vol. 70, no. 3, pp. 399-403.
Favia, G. ; Lumachi, F. ; Reale, F. ; Sommariva, A. ; D'Amico, D. F. / Iperparatiroidismo primitivo. Analisi critica di un'esperienza di 20 anni. In: Annali Italiani di Chirurgia. 1999 ; Vol. 70, No. 3. pp. 399-403.
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