Primary hyperparathyroidism. Our experience.

L. De Marinis, A. Mancini, R. Sciuto, F. Calabrò, P. Zuppi, C. Fiumara, A. Goglia, L. Sofo, R. Bellantone, F. Crucitti

Research output: Contribution to journalArticlepeer-review


We report our experience in the clinical presentation and management of 12 patients with primary hyperparathyroidism, who underwent successful surgery. Comparing our results with those previously reported in the literature, we have attempted to correlate the kind of parathyroid lesion, the magnitude of hypercalcemia and PTH increase, and clinical symptoms. Often these relationships are intriguing; we have tried to classify our patients describing four groups, according to clinical and humoral findings: 1) patients with very mild hypercalcemia and aspecific symptoms; 2) patients with a finding of recurrent hypercalcemia and prevalent renal involvement; 3) patients with severe hypercalcemia, plurisystemic involvement and general decay; 4) patients with medical emergencies. Finally, some considerations on rare histological pictures (hyperfunctioning carcinoma, oxyphil cell adenoma) are reported.

Original languageEnglish
Pages (from-to)107-111
Number of pages5
JournalMinerva Endocrinologica
Issue number3
Publication statusPublished - Jul 1991

ASJC Scopus subject areas

  • Medicine(all)


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