Primary intracranial fibrosarcoma

Gianni Bisogno, Jelena Roganovic, Modesto Carli, Giovanni Scarzello, Milena Calderone, Roberto Faggin, Giorgio Perilongo

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Introduction: Primary fibrosarcomas of the brain are very rare tumors, so that information regarding the treatment is scarce. We report the contributions that different therapeutic options made to the treatment of a child with one of these aggressive tumors. Case report: A 13-year-old boy underwent a complete resection of a left temporo-parietal mass that had been diagnosed as a fibrosarcoma by two independent pathologists. Adjuvant chemotherapy with vincristine, actinomycin-D, ifosfamide and Adriamycin was started, but after 3 months tumor relapse was evident. The boy subsequently received radiation therapy during which there was evidence of progressive tumor shrinkage. A second surgery was performed 6 months after radiotherapy and a small enhancing lesion, revealed to be gliosis, was resected. The child remains alive and well 44 months after diagnosis. Conclusion: Our experience supports the importance of total resection followed by radiation therapy, and radiotherapy should be started as soon as possible after surgical resection, rather than administering chemotherapy first.

Original languageEnglish
Pages (from-to)648-651
Number of pages4
JournalChild's Nervous System
Volume18
Issue number11
DOIs
Publication statusPublished - Nov 1 2002

Fingerprint

Fibrosarcoma
Radiotherapy
Neoplasms
Ifosfamide
Gliosis
Dactinomycin
Vincristine
Adjuvant Chemotherapy
Doxorubicin
Therapeutics
Recurrence
Drug Therapy
Brain

Keywords

  • Fibrosarcoma
  • Intracranial sarcoma

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Clinical Neurology

Cite this

Bisogno, G., Roganovic, J., Carli, M., Scarzello, G., Calderone, M., Faggin, R., & Perilongo, G. (2002). Primary intracranial fibrosarcoma. Child's Nervous System, 18(11), 648-651. https://doi.org/10.1007/s00381-002-0628-6

Primary intracranial fibrosarcoma. / Bisogno, Gianni; Roganovic, Jelena; Carli, Modesto; Scarzello, Giovanni; Calderone, Milena; Faggin, Roberto; Perilongo, Giorgio.

In: Child's Nervous System, Vol. 18, No. 11, 01.11.2002, p. 648-651.

Research output: Contribution to journalArticle

Bisogno, G, Roganovic, J, Carli, M, Scarzello, G, Calderone, M, Faggin, R & Perilongo, G 2002, 'Primary intracranial fibrosarcoma', Child's Nervous System, vol. 18, no. 11, pp. 648-651. https://doi.org/10.1007/s00381-002-0628-6
Bisogno G, Roganovic J, Carli M, Scarzello G, Calderone M, Faggin R et al. Primary intracranial fibrosarcoma. Child's Nervous System. 2002 Nov 1;18(11):648-651. https://doi.org/10.1007/s00381-002-0628-6
Bisogno, Gianni ; Roganovic, Jelena ; Carli, Modesto ; Scarzello, Giovanni ; Calderone, Milena ; Faggin, Roberto ; Perilongo, Giorgio. / Primary intracranial fibrosarcoma. In: Child's Nervous System. 2002 ; Vol. 18, No. 11. pp. 648-651.
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