Primary lymphoma of the heart. A case report and review of the literature

Giovanni Rolla, Maria Tiziana Bertero, Guglielmo Pastena, Nicoletta Tartaglia, Federica Corradi, Riccardo Casabona, Manuela Motta, Federico Caligaris-Cappio

Research output: Contribution to journalArticlepeer-review


Primary cardiac lymphoma (PCL) is a rare and usually fatal neoplasm, which may cause syncope, arrhythmia, heart failure and pericardial effusion as presenting clinical complaints. A case of PCL in a 72-year-old man with moderate aortic stenosis is presented. The patient was investigated because of pericardial effusion and diagnosis of diffuse large B-cell lymphoma was obtained by open-chest biopsy of the heart. Fatal ventricular arrhythmia developed the day after the first course of chemotherapy. Clinical presentations and diagnostic approach of this rare tumour are discussed. While chemotherapy is the only effective treatment of PCL, early post-chemotherapy phase should be considered critical in patients with PCL, as suggested by other reported fatal complications in this period.

Original languageEnglish
Pages (from-to)117-120
Number of pages4
JournalLeukemia Research
Issue number1
Publication statusPublished - 2002


  • Cardiac arrhythmia
  • Chemotherapy
  • Primary cardiac lymphoma

ASJC Scopus subject areas

  • Cancer Research
  • Hematology
  • Oncology


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