Primary malignant lymphoma located within extraocular muscles

C. Degli Angeli, E. Midena, M. Valenti, P. Boccato

Research output: Contribution to journalArticlepeer-review


Purpose. To describe three cases of primary orbital lymphoma of extraocular muscles and to discuss clinical significance of lymphoid infiltration of extraocular muscles. Methods. Three white males with a mean age of 55 years, presented long-lasting monolateral proptosis and impaired function of one extraocular muscle. A complete imaging and cytologic study was performad. Results. Computed tomography and/or magnetic resonance imaging showed a mass located within the involved muscle (lateral rectus in two cases and medial rectus in the third one). Cytologic diagnosis of malignant lymphoma was obtained through microscopic examination and immunocytochemistry performed on fine-needle aspiration biopsy (FNAB) specimens. A complete metastatic work-up excluded extra-orbital locations of the limphoma and local radiotherapy was completely successful. Conclusions. Primary location of malignant lymphoma within extraocular muscles is a rare event ant it has seldom been described (Ophthalmology' 94: 688, 1987) . Differential diagnosis from other causes of lympoid infiltration of extra-ocular muscles, particularly Graves' disease and idiopathic orbital myositis, is discussed. FNAB is a fundamental step in such a diagnosis.

Original languageEnglish
JournalInvestigative Ophthalmology and Visual Science
Issue number3
Publication statusPublished - Feb 15 1996

ASJC Scopus subject areas

  • Ophthalmology


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