Primary melanoma of the esophagus with non-metastatic dark lymph nodes in a female breast cancer patient

Nicola Solari, Mirko Acquati, Paola Queirolo, Mattia Stella, Carmine Di Somma, Mauro Truini, Ferdinando Cafiero

Research output: Contribution to journalArticle

Abstract

Background: Primary melanoma of the esophagus is a very rare and aggressive neoplasm; only a small number of patients survive more than 1 year after initial diagnosis. Case Report: We describe a case of primary melanoma of the esophagus in a woman with a history of invasive breast cancer. The patient suffered from dysphagic and dyspeptic disorders. The abdomen ultrasonography and the esophagogastroscopy showed a lesion located at the esophago-gastric junction extending to the gastric fundus. Histological and immunohistochemical studies revealed a primary esophageal infiltrating melanoma. A total gastrectomy and regional lymphadenectomy with a partial resection of the distal esophagus was performed. Results: During laparotomic exploration, numerous dark lymp hnodes were found. On frozen sections, surprisingly neither malignant cells nor melanin were detected in the lymph nodes. Resection margins were not involved with the tumor. Conclusion: Patient is still alive with no evidence of recurrence at 24 months after surgical treatment, alone.

Original languageEnglish
Pages (from-to)2849-2853
Number of pages5
JournalAnticancer Research
Volume27
Issue number4 C
Publication statusPublished - Jul 2007

Fingerprint

Esophagus
Melanoma
Lymph Nodes
Breast Neoplasms
Gastric Fundus
Melanins
Frozen Sections
Gastrectomy
Lymph Node Excision
Abdomen
Ultrasonography
Neoplasms
Stomach
Recurrence
Therapeutics
Margins of Excision

Keywords

  • Breast cancer
  • Esophagectomy
  • Esophagus
  • Lymph nodes
  • Melanoma

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

Cite this

Solari, N., Acquati, M., Queirolo, P., Stella, M., Di Somma, C., Truini, M., & Cafiero, F. (2007). Primary melanoma of the esophagus with non-metastatic dark lymph nodes in a female breast cancer patient. Anticancer Research, 27(4 C), 2849-2853.

Primary melanoma of the esophagus with non-metastatic dark lymph nodes in a female breast cancer patient. / Solari, Nicola; Acquati, Mirko; Queirolo, Paola; Stella, Mattia; Di Somma, Carmine; Truini, Mauro; Cafiero, Ferdinando.

In: Anticancer Research, Vol. 27, No. 4 C, 07.2007, p. 2849-2853.

Research output: Contribution to journalArticle

Solari, N, Acquati, M, Queirolo, P, Stella, M, Di Somma, C, Truini, M & Cafiero, F 2007, 'Primary melanoma of the esophagus with non-metastatic dark lymph nodes in a female breast cancer patient', Anticancer Research, vol. 27, no. 4 C, pp. 2849-2853.
Solari N, Acquati M, Queirolo P, Stella M, Di Somma C, Truini M et al. Primary melanoma of the esophagus with non-metastatic dark lymph nodes in a female breast cancer patient. Anticancer Research. 2007 Jul;27(4 C):2849-2853.
Solari, Nicola ; Acquati, Mirko ; Queirolo, Paola ; Stella, Mattia ; Di Somma, Carmine ; Truini, Mauro ; Cafiero, Ferdinando. / Primary melanoma of the esophagus with non-metastatic dark lymph nodes in a female breast cancer patient. In: Anticancer Research. 2007 ; Vol. 27, No. 4 C. pp. 2849-2853.
@article{446bc82c7bb64b558a5b69707666c85a,
title = "Primary melanoma of the esophagus with non-metastatic dark lymph nodes in a female breast cancer patient",
abstract = "Background: Primary melanoma of the esophagus is a very rare and aggressive neoplasm; only a small number of patients survive more than 1 year after initial diagnosis. Case Report: We describe a case of primary melanoma of the esophagus in a woman with a history of invasive breast cancer. The patient suffered from dysphagic and dyspeptic disorders. The abdomen ultrasonography and the esophagogastroscopy showed a lesion located at the esophago-gastric junction extending to the gastric fundus. Histological and immunohistochemical studies revealed a primary esophageal infiltrating melanoma. A total gastrectomy and regional lymphadenectomy with a partial resection of the distal esophagus was performed. Results: During laparotomic exploration, numerous dark lymp hnodes were found. On frozen sections, surprisingly neither malignant cells nor melanin were detected in the lymph nodes. Resection margins were not involved with the tumor. Conclusion: Patient is still alive with no evidence of recurrence at 24 months after surgical treatment, alone.",
keywords = "Breast cancer, Esophagectomy, Esophagus, Lymph nodes, Melanoma",
author = "Nicola Solari and Mirko Acquati and Paola Queirolo and Mattia Stella and {Di Somma}, Carmine and Mauro Truini and Ferdinando Cafiero",
year = "2007",
month = "7",
language = "English",
volume = "27",
pages = "2849--2853",
journal = "Anticancer Research",
issn = "0250-7005",
publisher = "International Institute of Anticancer Research",
number = "4 C",

}

TY - JOUR

T1 - Primary melanoma of the esophagus with non-metastatic dark lymph nodes in a female breast cancer patient

AU - Solari, Nicola

AU - Acquati, Mirko

AU - Queirolo, Paola

AU - Stella, Mattia

AU - Di Somma, Carmine

AU - Truini, Mauro

AU - Cafiero, Ferdinando

PY - 2007/7

Y1 - 2007/7

N2 - Background: Primary melanoma of the esophagus is a very rare and aggressive neoplasm; only a small number of patients survive more than 1 year after initial diagnosis. Case Report: We describe a case of primary melanoma of the esophagus in a woman with a history of invasive breast cancer. The patient suffered from dysphagic and dyspeptic disorders. The abdomen ultrasonography and the esophagogastroscopy showed a lesion located at the esophago-gastric junction extending to the gastric fundus. Histological and immunohistochemical studies revealed a primary esophageal infiltrating melanoma. A total gastrectomy and regional lymphadenectomy with a partial resection of the distal esophagus was performed. Results: During laparotomic exploration, numerous dark lymp hnodes were found. On frozen sections, surprisingly neither malignant cells nor melanin were detected in the lymph nodes. Resection margins were not involved with the tumor. Conclusion: Patient is still alive with no evidence of recurrence at 24 months after surgical treatment, alone.

AB - Background: Primary melanoma of the esophagus is a very rare and aggressive neoplasm; only a small number of patients survive more than 1 year after initial diagnosis. Case Report: We describe a case of primary melanoma of the esophagus in a woman with a history of invasive breast cancer. The patient suffered from dysphagic and dyspeptic disorders. The abdomen ultrasonography and the esophagogastroscopy showed a lesion located at the esophago-gastric junction extending to the gastric fundus. Histological and immunohistochemical studies revealed a primary esophageal infiltrating melanoma. A total gastrectomy and regional lymphadenectomy with a partial resection of the distal esophagus was performed. Results: During laparotomic exploration, numerous dark lymp hnodes were found. On frozen sections, surprisingly neither malignant cells nor melanin were detected in the lymph nodes. Resection margins were not involved with the tumor. Conclusion: Patient is still alive with no evidence of recurrence at 24 months after surgical treatment, alone.

KW - Breast cancer

KW - Esophagectomy

KW - Esophagus

KW - Lymph nodes

KW - Melanoma

UR - http://www.scopus.com/inward/record.url?scp=34547822610&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=34547822610&partnerID=8YFLogxK

M3 - Article

C2 - 17695459

AN - SCOPUS:34547822610

VL - 27

SP - 2849

EP - 2853

JO - Anticancer Research

JF - Anticancer Research

SN - 0250-7005

IS - 4 C

ER -