Primary monotypic epithelioid angiomyolipoma of bone

L. Insabato, G. De Rosa, L. M. Terracciano, F. Fazioli, F. Di Santo, J. Rosai

Research output: Contribution to journalArticlepeer-review


Aims: Monotypic epithelioid angiomyolipoma is a distinct and definable variant of angiomyolipoma, composed of monomorphous epithelioid cells that show HMB45 immunoreactivity. Angiomyolipoma, including its morphological variants, belongs to the family of perivascular epithelioid cell tumour. Methods and results: The tumour was examined using immunohistochemical staining and by transmission electron microscopy. Neoplastic cells showed a cytoplasmic granular positivity for HMB45. Conclusions: Extrarenal angiomyolipomas are rare and, to the best of our knowledge, this is the first reported case of a primary monotypic epithelioid angiomyolipoma of bone in a patient without evidence of tuberous sclerosis.

Original languageEnglish
Pages (from-to)286-290
Number of pages5
Issue number3
Publication statusPublished - 2002


  • Bone
  • Epithelioid angiomyolipoma
  • Monotypic

ASJC Scopus subject areas

  • Anatomy
  • Pathology and Forensic Medicine
  • Cell Biology


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