Primary pericardial mesothelioma in an asbestos-exposed patient with previous heart surgery

Clara Rizzardi, Elena Barresi, Alessandro Brollo, Paolo Cassetti, Manuela Schneider, Mauro Melato

Research output: Contribution to journalArticle

Abstract

We present a case of primary pericardial mesothelioma occurring in an asbestos-exposed 67-year-old man who underwent four aortocoronary bypass grafting seven years prior to the onset of the mesothelioma. Primary pericardial mesothelioma is a rare tumor whose association with asbestos is more infrequent than that of the much more common pleural form. Factors other than asbestos that may play a role include genetic predisposition, immune impairment, infections, radiation, dietary factors, and recurrent serosal inflammation. We consider that, in the presented case, inflammation and healing resulting from pericardiotomy might have had a synergistic effect with asbestos in the pathogenesis of the tumor. To our knowledge, this is the first reported case of primary pericardial mesothelioma arising in a patient exposed to asbestos who previously underwent cardiac surgery.

Original languageEnglish
Pages (from-to)1323-1325
Number of pages3
JournalAnticancer Research
Volume30
Issue number4
Publication statusPublished - Apr 2010

Keywords

  • Asbestos
  • Inflammation
  • Mesothelioma
  • Pericardial mesothelioma

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

Fingerprint Dive into the research topics of 'Primary pericardial mesothelioma in an asbestos-exposed patient with previous heart surgery'. Together they form a unique fingerprint.

  • Cite this

    Rizzardi, C., Barresi, E., Brollo, A., Cassetti, P., Schneider, M., & Melato, M. (2010). Primary pericardial mesothelioma in an asbestos-exposed patient with previous heart surgery. Anticancer Research, 30(4), 1323-1325.