TY - JOUR
T1 - Primary Prophylaxis of Invasive Fungal Diseases in Allogeneic Stem Cell Transplantation
T2 - Revised Recommendations from a Consensus Process by Gruppo Italiano Trapianto Midollo Osseo (GITMO)
AU - Girmenia, Corrado
AU - Barosi, Giovanni
AU - Piciocchi, Alfonso
AU - Arcese, William
AU - Aversa, Franco
AU - Bacigalupo, Andrea
AU - Bandini, Giuseppe
AU - Bosi, Alberto
AU - Busca, Alessandro
AU - Castagnola, Elio
AU - Caselli, Desiree
AU - Cesaro, Simone
AU - Ciceri, Fabio
AU - Locasciulli, Anna
AU - Locatelli, Franco
AU - Mikulska, Malgorzata
AU - Pagano, Livio
AU - Prete, Arcangelo
AU - Raiola, Anna Maria
AU - Rambaldi, Alessandro
PY - 2014
Y1 - 2014
N2 - This document updates and expands the recommendations on primary prophylaxis of invasive fungal diseases (IFD) in allogeneic hematopoietic stem cell transplantation (allo-HSCT) recipients, published in 2009 by the Gruppo Italiano Trapianto Midollo Osseo (GITMO). A consensus process was undertaken to describe and evaluate current information and practice regarding risk stratification and primary antifungal prophylaxis during the pre-engraftment and postengraftment phases after allo-HSCT. The revised recommendations were based on the evaluation of recent literature including a large, prospective, multicenter epidemiological study of allo-HSCT recipients conducted among the GITMO transplantation centers during the period of 2008 to 2010. It is intended as a guide for the identification of types and phases of transplantation at low, standard, and high risk for IFD, according to the underlying disease, transplantation, and post-transplantation factors. The risk stratification was the critical determinant of the primary antifungal approach for allo-HSCT recipients.
AB - This document updates and expands the recommendations on primary prophylaxis of invasive fungal diseases (IFD) in allogeneic hematopoietic stem cell transplantation (allo-HSCT) recipients, published in 2009 by the Gruppo Italiano Trapianto Midollo Osseo (GITMO). A consensus process was undertaken to describe and evaluate current information and practice regarding risk stratification and primary antifungal prophylaxis during the pre-engraftment and postengraftment phases after allo-HSCT. The revised recommendations were based on the evaluation of recent literature including a large, prospective, multicenter epidemiological study of allo-HSCT recipients conducted among the GITMO transplantation centers during the period of 2008 to 2010. It is intended as a guide for the identification of types and phases of transplantation at low, standard, and high risk for IFD, according to the underlying disease, transplantation, and post-transplantation factors. The risk stratification was the critical determinant of the primary antifungal approach for allo-HSCT recipients.
KW - Allogeneic hematopoietic stem cell transplantation (HSCT)
KW - Antifungal prophylaxis
KW - Consensus
KW - Fungal infections
UR - http://www.scopus.com/inward/record.url?scp=84904040438&partnerID=8YFLogxK
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U2 - 10.1016/j.bbmt.2014.02.018
DO - 10.1016/j.bbmt.2014.02.018
M3 - Article
C2 - 24582783
AN - SCOPUS:84904040438
VL - 20
SP - 1080
EP - 1088
JO - Biology of Blood and Marrow Transplantation
JF - Biology of Blood and Marrow Transplantation
SN - 1083-8791
IS - 8
ER -