Abstract
| Original language | English |
|---|---|
| Pages (from-to) | 505-510 |
| Number of pages | 6 |
| Journal | Andrology |
| Volume | 5 |
| Issue number | 3 |
| DOIs | |
| Publication status | Published - 2017 |
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Primary, secondary and compensated hypogonadism: a novel risk stratification for infertile men. / Ventimiglia, E; Ippolito, Silvia; Capogrosso, P; Pederzoli, F; Cazzaniga, W; Boeri, Luca; Cavarretta, I; Alfano, M; Viganò, P; Montorsi, F; Salonia, A.
In: Andrology, Vol. 5, No. 3, 2017, p. 505-510.Research output: Contribution to journal › Article
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TY - JOUR
T1 - Primary, secondary and compensated hypogonadism: a novel risk stratification for infertile men
AU - Ventimiglia, E
AU - Ippolito, Silvia
AU - Capogrosso, P
AU - Pederzoli, F
AU - Cazzaniga, W
AU - Boeri, Luca
AU - Cavarretta, I
AU - Alfano, M
AU - Viganò, P
AU - Montorsi, F
AU - Salonia, A
PY - 2017
Y1 - 2017
N2 - Recently, the cohort of men from the European Male Ageing Study has been stratified into different categories distinguishing primary, secondary and compensated hypogonadism. A similar classification has not yet been applied to the infertile population. We performed a cross-sectional study enrolling 786 consecutive Caucasian-European infertile men segregated into eugonadal [normal serum total testosterone (≥3.03 ng/mL) and normal luteinizing hormone (≤9.4 mU/mL)], secondary (low total testosterone, low/normal luteinizing hormone), primary (low total testosterone, elevated luteinizing hormone) and compensated hypogonadism (normal total testosterone; elevated luteinizing hormone). In this cross-sectional study, logistic regression models tested the association between semen parameters, clinical characteristics and the defined gonadal status. Eugonadism, secondary, primary and compensated hypogonadism were found in 80, 15, 2, and 3% of men respectively. Secondary hypogonadal men were at highest risk for obesity [OR (95% CI): 3.48 (1.98–6.01)]. Primary hypogonadal men were those at highest risk for azoospermia [24.54 (6.39–161.39)] and testicular volume
AB - Recently, the cohort of men from the European Male Ageing Study has been stratified into different categories distinguishing primary, secondary and compensated hypogonadism. A similar classification has not yet been applied to the infertile population. We performed a cross-sectional study enrolling 786 consecutive Caucasian-European infertile men segregated into eugonadal [normal serum total testosterone (≥3.03 ng/mL) and normal luteinizing hormone (≤9.4 mU/mL)], secondary (low total testosterone, low/normal luteinizing hormone), primary (low total testosterone, elevated luteinizing hormone) and compensated hypogonadism (normal total testosterone; elevated luteinizing hormone). In this cross-sectional study, logistic regression models tested the association between semen parameters, clinical characteristics and the defined gonadal status. Eugonadism, secondary, primary and compensated hypogonadism were found in 80, 15, 2, and 3% of men respectively. Secondary hypogonadal men were at highest risk for obesity [OR (95% CI): 3.48 (1.98–6.01)]. Primary hypogonadal men were those at highest risk for azoospermia [24.54 (6.39–161.39)] and testicular volume
U2 - 10.1111/andr.12335
DO - 10.1111/andr.12335
M3 - Article
VL - 5
SP - 505
EP - 510
JO - Andrology
JF - Andrology
SN - 2047-2919
IS - 3
ER -