TY - JOUR
T1 - Primary solitary intracranial melanoma
T2 - Case report and review of the literature
AU - Rodriguez y Baena, Riccardo
AU - Gaetani, Paolo
AU - Danova, Marco
AU - Bosi, Federica
AU - Zappoli, Federico
PY - 1992
Y1 - 1992
N2 - Among CNS tumors, intracranial melanomas represent a subject of interest for neurooncologists and neurosurgeons because clinical and radiological patterns of these tumors can mimic the presence of meningiomas, and in spite of their malignant behavior they can be satisfactorily treated. In the present report we describe a new case of primary intracranial melanoma that displayed some radiological features of meningioma; we review the clinical features of 80 previously well-documented cases. The importance of neuroradiological and histochemical (S-100 protein, antimelanin antibodies, proliferating cell nuclear antigen staining) methods and of flow cytometry in helping with histopathological examination is stressed. Review of the clinical histories demonstrates that surgical excision is recommended in most cases, depending on tumor location, and that if total removal is performed, longterm disease-free periods can be attained.
AB - Among CNS tumors, intracranial melanomas represent a subject of interest for neurooncologists and neurosurgeons because clinical and radiological patterns of these tumors can mimic the presence of meningiomas, and in spite of their malignant behavior they can be satisfactorily treated. In the present report we describe a new case of primary intracranial melanoma that displayed some radiological features of meningioma; we review the clinical features of 80 previously well-documented cases. The importance of neuroradiological and histochemical (S-100 protein, antimelanin antibodies, proliferating cell nuclear antigen staining) methods and of flow cytometry in helping with histopathological examination is stressed. Review of the clinical histories demonstrates that surgical excision is recommended in most cases, depending on tumor location, and that if total removal is performed, longterm disease-free periods can be attained.
KW - Flow cytometry
KW - Immunohistochemistry
KW - Intracranial melanoma
KW - Surgery
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U2 - 10.1016/0090-3019(92)90208-5
DO - 10.1016/0090-3019(92)90208-5
M3 - Article
C2 - 1615371
AN - SCOPUS:0026664246
VL - 38
SP - 26
EP - 37
JO - Surgical Neurology
JF - Surgical Neurology
SN - 0090-3019
IS - 1
ER -