Primary vitrectomy with Densiron-68 for rhegmatogenous retinal detachment

M. R. Romano, T. Stappler, J. Marticorena, C. Groenewald, I. Pearce, S. K. Gibran, D. Wong, H. Heimann

Research output: Contribution to journalArticle

36 Citations (Scopus)

Abstract

Background: To report a retrospective non-comparative interventional study on the effectiveness and ocular tolerance of a heavy silicone oil tamponade (HSO, Densiron-68) for primary inferior rhegmatogenous retinal detachment (RRD). Methods: Forty-one eyes of 41 consecutive patients were recruited between January 2004 and August 2006. Primary vitrectomy with Densiron-68, a heavy silicone oil, was used in all cases. Inclusion criteria were primary RRD with at least one retinal break between 4 and 8 clock hours. The study protocol consisted of a minimum of eight clinic visits: baseline, surgery, 1 week, 1 month and 3 months after the initial surgery; removal of oil and 1 week, 1 month and 3 months postoperatively. The primary endpoint was anatomical re-attachment of the retina. Cases were judged successful when there was reattachment of the retina in the absence of any tamponade agent. The secondary endpoint was to record the visual function and any complications arising from the surgery. Out of 41 patients initially included in the study, 33 completed all follow-up visits. Results: Anatomical success was achieved in 91% of cases (30 out of 33) with one retinal operation, and rose to 94% (31 out of 33) with additional surgery. Mean visual acuity improved from logMAR 1.19 (SD 0.9) to 0.5 (SD 0.51, p = 0.001). No significant ocular hypertension, clinically significant emulsification of the tamponade or inflammation developed during follow-up. Conclusion: With Densiron-68, high anatomical and functional success rates can be achieved with primary vitrectomy for RRD and predominantly inferior pathology.

Original languageEnglish
Pages (from-to)1541-1546
Number of pages6
JournalGraefe's Archive for Clinical and Experimental Ophthalmology
Volume246
Issue number11
DOIs
Publication statusPublished - 2008

Fingerprint

Vitrectomy
Retinal Detachment
Retina
Ocular Hypertension
Retinal Perforations
Ambulatory Care
Visual Acuity
Oils
Pathology
Inflammation
densiron-68
densiron

Keywords

  • Heavy silicon oil
  • Perfluorohexyloctane
  • Primary inferior
  • Rhegmatogenous retinal detachment
  • Semifluorinated alkanes

ASJC Scopus subject areas

  • Ophthalmology
  • Sensory Systems
  • Cellular and Molecular Neuroscience

Cite this

Romano, M. R., Stappler, T., Marticorena, J., Groenewald, C., Pearce, I., Gibran, S. K., ... Heimann, H. (2008). Primary vitrectomy with Densiron-68 for rhegmatogenous retinal detachment. Graefe's Archive for Clinical and Experimental Ophthalmology, 246(11), 1541-1546. https://doi.org/10.1007/s00417-008-0894-4

Primary vitrectomy with Densiron-68 for rhegmatogenous retinal detachment. / Romano, M. R.; Stappler, T.; Marticorena, J.; Groenewald, C.; Pearce, I.; Gibran, S. K.; Wong, D.; Heimann, H.

In: Graefe's Archive for Clinical and Experimental Ophthalmology, Vol. 246, No. 11, 2008, p. 1541-1546.

Research output: Contribution to journalArticle

Romano, MR, Stappler, T, Marticorena, J, Groenewald, C, Pearce, I, Gibran, SK, Wong, D & Heimann, H 2008, 'Primary vitrectomy with Densiron-68 for rhegmatogenous retinal detachment', Graefe's Archive for Clinical and Experimental Ophthalmology, vol. 246, no. 11, pp. 1541-1546. https://doi.org/10.1007/s00417-008-0894-4
Romano, M. R. ; Stappler, T. ; Marticorena, J. ; Groenewald, C. ; Pearce, I. ; Gibran, S. K. ; Wong, D. ; Heimann, H. / Primary vitrectomy with Densiron-68 for rhegmatogenous retinal detachment. In: Graefe's Archive for Clinical and Experimental Ophthalmology. 2008 ; Vol. 246, No. 11. pp. 1541-1546.
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