Primary Whipple disease of the Central Nervous System presenting with rhombencephalitis

Claudia Balducci, Sergio Foresti, Alessandra Ciervo, Fabiola Mancini, Giulia Nastasi, Laura Marzorati, Andrea Gori, Carlo Ferrarese, Ildebrando Appollonio, Anna Maria Peri

Research output: Contribution to journalArticlepeer-review

Abstract

Primary Whipple disease of the Central Nervous System is a rare entity whose outcome might be fatal if not promptly diagnosed and treated. Few cases are reported in the literature with heterogeneous clinical and radiological presentations which often make the diagnosis extremely challenging. We report a case of primary Whipple disease of the Central Nervous System presenting with rhombencephalitis in a female patient in immunosuppressive treatment for rheumatoid arthritis. We describe the management of our patient and discuss the features of this rare clinical entity. (C) 2019 The Authors. Published by Elsevier Ltd on behalf of International Society for Infectious Diseases.
Original languageEnglish
Pages (from-to)149-151
Number of pages3
JournalInt. J. Infect. Dis.
Volume88
DOIs
Publication statusPublished - Nov 1 2019

Keywords

  • Primary Whipple disease
  • Rhombencephalitis
  • Immunocompromised host

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