Primary Whipple disease of the Central Nervous System presenting with rhombencephalitis

Claudia Balducci; Sergio Foresti; Alessandra Ciervo; Fabiola Mancini; Giulia Nastasi; Laura Marzorati; Andrea Gori; Carlo Ferrarese; Ildebrando Appollonio; Anna Maria Peri

doi:10.1016/j.ijid.2019.08.019

Primary Whipple disease of the Central Nervous System presenting with rhombencephalitis

Claudia Balducci, Sergio Foresti, Alessandra Ciervo, Fabiola Mancini, Giulia Nastasi, Laura Marzorati, Andrea Gori, Carlo Ferrarese, Ildebrando Appollonio, Anna Maria Peri

Research output: Contribution to journal › Article › peer-review

Abstract

Primary Whipple disease of the Central Nervous System is a rare entity whose outcome might be fatal if not promptly diagnosed and treated. Few cases are reported in the literature with heterogeneous clinical and radiological presentations which often make the diagnosis extremely challenging. We report a case of primary Whipple disease of the Central Nervous System presenting with rhombencephalitis in a female patient in immunosuppressive treatment for rheumatoid arthritis. We describe the management of our patient and discuss the features of this rare clinical entity. (C) 2019 The Authors. Published by Elsevier Ltd on behalf of International Society for Infectious Diseases.

Original language	English
Pages (from-to)	149-151
Number of pages	3
Journal	Int. J. Infect. Dis.
Volume	88
DOIs	https://doi.org/10.1016/j.ijid.2019.08.019
Publication status	Published - Nov 1 2019

Keywords

Primary Whipple disease
Rhombencephalitis
Immunocompromised host

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10.1016/j.ijid.2019.08.019

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Primary Whipple disease of the Central Nervous System presenting with rhombencephalitis. / Balducci, Claudia; Foresti, Sergio; Ciervo, Alessandra ; Mancini, Fabiola; Nastasi, Giulia; Marzorati, Laura; Gori, Andrea; Ferrarese, Carlo; Appollonio, Ildebrando; Peri, Anna Maria.

In: Int. J. Infect. Dis., Vol. 88, 01.11.2019, p. 149-151.

Research output: Contribution to journal › Article › peer-review

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abstract = "Primary Whipple disease of the Central Nervous System is a rare entity whose outcome might be fatal if not promptly diagnosed and treated. Few cases are reported in the literature with heterogeneous clinical and radiological presentations which often make the diagnosis extremely challenging. We report a case of primary Whipple disease of the Central Nervous System presenting with rhombencephalitis in a female patient in immunosuppressive treatment for rheumatoid arthritis. We describe the management of our patient and discuss the features of this rare clinical entity. (C) 2019 The Authors. Published by Elsevier Ltd on behalf of International Society for Infectious Diseases.",

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author = "Claudia Balducci and Sergio Foresti and Alessandra Ciervo and Fabiola Mancini and Giulia Nastasi and Laura Marzorati and Andrea Gori and Carlo Ferrarese and Ildebrando Appollonio and Peri, {Anna Maria}",

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AU - Balducci, Claudia

AU - Foresti, Sergio

AU - Ciervo, Alessandra

AU - Mancini, Fabiola

AU - Nastasi, Giulia

AU - Marzorati, Laura

AU - Gori, Andrea

AU - Ferrarese, Carlo

AU - Appollonio, Ildebrando

AU - Peri, Anna Maria

PY - 2019/11/1

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N2 - Primary Whipple disease of the Central Nervous System is a rare entity whose outcome might be fatal if not promptly diagnosed and treated. Few cases are reported in the literature with heterogeneous clinical and radiological presentations which often make the diagnosis extremely challenging. We report a case of primary Whipple disease of the Central Nervous System presenting with rhombencephalitis in a female patient in immunosuppressive treatment for rheumatoid arthritis. We describe the management of our patient and discuss the features of this rare clinical entity. (C) 2019 The Authors. Published by Elsevier Ltd on behalf of International Society for Infectious Diseases.

AB - Primary Whipple disease of the Central Nervous System is a rare entity whose outcome might be fatal if not promptly diagnosed and treated. Few cases are reported in the literature with heterogeneous clinical and radiological presentations which often make the diagnosis extremely challenging. We report a case of primary Whipple disease of the Central Nervous System presenting with rhombencephalitis in a female patient in immunosuppressive treatment for rheumatoid arthritis. We describe the management of our patient and discuss the features of this rare clinical entity. (C) 2019 The Authors. Published by Elsevier Ltd on behalf of International Society for Infectious Diseases.

KW - Primary Whipple disease

KW - Rhombencephalitis

KW - Immunocompromised host

U2 - 10.1016/j.ijid.2019.08.019

DO - 10.1016/j.ijid.2019.08.019

M3 - Article

VL - 88

SP - 149

EP - 151

JO - Int. J. Infect. Dis.

JF - Int. J. Infect. Dis.

SN - 1201-9712

ER -

Primary Whipple disease of the Central Nervous System presenting with rhombencephalitis

Abstract

Keywords

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