Principi per un uso razionale dei farmaci nel paziente anziano con cachessia neoplastica

Translated title of the contribution: Principles for a rationale administration of drugs in elderly patients with neoplastic cachexia

Dario Cova, Vito Lorusso, Modesto D'Aprile, Nicola Silvestris

Research output: Contribution to journalArticle

Abstract

Neoplastic cachexia is a complex and multifactorial syndrome able to affect drug efficacy mainly in elderly oncological patient in relation both to organ insufficiencies and to comorbidities. Use of antitumoural drugs in this phase of disease, particularly in elderly patients, is extremely complicated because of the clear implications on the quality of residual life. In such context a good knowledge of both pharmacokinetic and pharmacodynamic characteristics can be of great help in decision-making procedure.

Original languageItalian
Pages (from-to)109-114
Number of pages6
JournalTrends in Medicine
Volume5
Issue number2
Publication statusPublished - Apr 2005

Fingerprint

Cachexia
Pharmaceutical Preparations
Comorbidity
Decision Making
Pharmacokinetics
Quality of Life

ASJC Scopus subject areas

  • Internal Medicine
  • Pharmacology (medical)

Cite this

Principi per un uso razionale dei farmaci nel paziente anziano con cachessia neoplastica. / Cova, Dario; Lorusso, Vito; D'Aprile, Modesto; Silvestris, Nicola.

In: Trends in Medicine, Vol. 5, No. 2, 04.2005, p. 109-114.

Research output: Contribution to journalArticle

@article{b06877be0b434f7a88697565b470a447,
title = "Principi per un uso razionale dei farmaci nel paziente anziano con cachessia neoplastica",
abstract = "Neoplastic cachexia is a complex and multifactorial syndrome able to affect drug efficacy mainly in elderly oncological patient in relation both to organ insufficiencies and to comorbidities. Use of antitumoural drugs in this phase of disease, particularly in elderly patients, is extremely complicated because of the clear implications on the quality of residual life. In such context a good knowledge of both pharmacokinetic and pharmacodynamic characteristics can be of great help in decision-making procedure.",
keywords = "Cachexia and neoplastic, Elderly, Pharmacodynamic, Pharmacokinetic",
author = "Dario Cova and Vito Lorusso and Modesto D'Aprile and Nicola Silvestris",
year = "2005",
month = "4",
language = "Italian",
volume = "5",
pages = "109--114",
journal = "Trends in Medicine",
issn = "1594-2848",
publisher = "Pharma Project Group Edizioni Scientifiche (PPG)",
number = "2",

}

TY - JOUR

T1 - Principi per un uso razionale dei farmaci nel paziente anziano con cachessia neoplastica

AU - Cova, Dario

AU - Lorusso, Vito

AU - D'Aprile, Modesto

AU - Silvestris, Nicola

PY - 2005/4

Y1 - 2005/4

N2 - Neoplastic cachexia is a complex and multifactorial syndrome able to affect drug efficacy mainly in elderly oncological patient in relation both to organ insufficiencies and to comorbidities. Use of antitumoural drugs in this phase of disease, particularly in elderly patients, is extremely complicated because of the clear implications on the quality of residual life. In such context a good knowledge of both pharmacokinetic and pharmacodynamic characteristics can be of great help in decision-making procedure.

AB - Neoplastic cachexia is a complex and multifactorial syndrome able to affect drug efficacy mainly in elderly oncological patient in relation both to organ insufficiencies and to comorbidities. Use of antitumoural drugs in this phase of disease, particularly in elderly patients, is extremely complicated because of the clear implications on the quality of residual life. In such context a good knowledge of both pharmacokinetic and pharmacodynamic characteristics can be of great help in decision-making procedure.

KW - Cachexia and neoplastic

KW - Elderly

KW - Pharmacodynamic

KW - Pharmacokinetic

UR - http://www.scopus.com/inward/record.url?scp=18744367810&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=18744367810&partnerID=8YFLogxK

M3 - Articolo

VL - 5

SP - 109

EP - 114

JO - Trends in Medicine

JF - Trends in Medicine

SN - 1594-2848

IS - 2

ER -