Probiotics and health: An evidence-based review

Paolo Aureli, Lucio Capurso, Anna Maria Castellazzi, Mario Clerici, Marcello Giovannini, Lorenzo Morelli, Andrea Poli, Fabrizio Pregliasco, Filippo Salvini, Gian Vincenzo Zuccotti

Research output: Contribution to journalArticle

149 Citations (Scopus)

Abstract

The intestinal microbiota is an ecosystem formed by a variety of ecological niches, made of several bacterial species and a very large amount of strains. The microbiota is in close contact with the intestinal mucosa or epithelial interface which is, after the respiratory area, the largest surface of the body, occupying approximately 250-400 m2. The physiological activities of the microbiota are manifold and are just being unraveled. Based on the observations of the multiple roles played by the microbiota in health and disease, the notion of modifying it with appropriate formulations, i.e. probiotics, is being tested in several settings. This review summarizes the current knowledge on probiotics and discusses both limitations and acquired evidence to support their use in preventive and therapeutic medicine.

Original languageEnglish
Pages (from-to)366-376
Number of pages11
JournalPharmacological Research
Volume63
Issue number5
DOIs
Publication statusPublished - May 2011

Fingerprint

Microbiota
Probiotics
Health
Preventive Medicine
Body Surface Area
Intestinal Mucosa
Ecosystem
Therapeutics

Keywords

  • Immune system
  • Microbiota
  • Probiotics

ASJC Scopus subject areas

  • Pharmacology

Cite this

Aureli, P., Capurso, L., Castellazzi, A. M., Clerici, M., Giovannini, M., Morelli, L., ... Zuccotti, G. V. (2011). Probiotics and health: An evidence-based review. Pharmacological Research, 63(5), 366-376. https://doi.org/10.1016/j.phrs.2011.02.006

Probiotics and health : An evidence-based review. / Aureli, Paolo; Capurso, Lucio; Castellazzi, Anna Maria; Clerici, Mario; Giovannini, Marcello; Morelli, Lorenzo; Poli, Andrea; Pregliasco, Fabrizio; Salvini, Filippo; Zuccotti, Gian Vincenzo.

In: Pharmacological Research, Vol. 63, No. 5, 05.2011, p. 366-376.

Research output: Contribution to journalArticle

Aureli, P, Capurso, L, Castellazzi, AM, Clerici, M, Giovannini, M, Morelli, L, Poli, A, Pregliasco, F, Salvini, F & Zuccotti, GV 2011, 'Probiotics and health: An evidence-based review', Pharmacological Research, vol. 63, no. 5, pp. 366-376. https://doi.org/10.1016/j.phrs.2011.02.006
Aureli P, Capurso L, Castellazzi AM, Clerici M, Giovannini M, Morelli L et al. Probiotics and health: An evidence-based review. Pharmacological Research. 2011 May;63(5):366-376. https://doi.org/10.1016/j.phrs.2011.02.006
Aureli, Paolo ; Capurso, Lucio ; Castellazzi, Anna Maria ; Clerici, Mario ; Giovannini, Marcello ; Morelli, Lorenzo ; Poli, Andrea ; Pregliasco, Fabrizio ; Salvini, Filippo ; Zuccotti, Gian Vincenzo. / Probiotics and health : An evidence-based review. In: Pharmacological Research. 2011 ; Vol. 63, No. 5. pp. 366-376.
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