Abstract
Atopic disease and eczema are heterogeneous disorders resulting from complex multifactorial interactions. Several studies highlighted the role of gut mucosa in protecting the host from pathogens, regulating the tolerance to them; so a gut weaken barrier may lead to an aberrant immune response and to the release of proinflammatory cytokines, which compromise, in turn, the barrier functionality. A link between allergy and eczema onset and the gut microbiota composition exist, and in particular, it is evident that some microorganisms are able to influence the immune response. For this reason, there is great interest in the beneficial role of probiotics in preventing and treating allergies and eczema. The probiotic benefits depend on many factors, such as the bacterial strain and the pathology. This review helps to understand the role of probiotics in allergy and eczema, highlighting their role in the prevention and treatment of the aforementioned diseases.
| Language | English |
|---|---|
| Title of host publication | Probiotics, Prebiotics, and Synbiotics: Bioactive Foods in Health Promotion |
| Publisher | Elsevier Inc. |
| Pages | 831-837 |
| Number of pages | 7 |
| ISBN (Print) | 9780128023716, 9780128021897 |
| DOIs | |
| Publication status | Published - Oct 8 2015 |
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Keywords
- Allergy
- Gut
- Probiotics
- Th1
- Th2
ASJC Scopus subject areas
- Medicine(all)
Cite this
Probiotics : Immunomodulatory properties in allergy and eczema. / Drago, Lorenzo; Toscano, Marco.
Probiotics, Prebiotics, and Synbiotics: Bioactive Foods in Health Promotion. Elsevier Inc., 2015. p. 831-837.Research output: Chapter in Book/Report/Conference proceeding › Chapter
}
TY - CHAP
T1 - Probiotics
T2 - Immunomodulatory properties in allergy and eczema
AU - Drago, Lorenzo
AU - Toscano, Marco
PY - 2015/10/8
Y1 - 2015/10/8
N2 - Atopic disease and eczema are heterogeneous disorders resulting from complex multifactorial interactions. Several studies highlighted the role of gut mucosa in protecting the host from pathogens, regulating the tolerance to them; so a gut weaken barrier may lead to an aberrant immune response and to the release of proinflammatory cytokines, which compromise, in turn, the barrier functionality. A link between allergy and eczema onset and the gut microbiota composition exist, and in particular, it is evident that some microorganisms are able to influence the immune response. For this reason, there is great interest in the beneficial role of probiotics in preventing and treating allergies and eczema. The probiotic benefits depend on many factors, such as the bacterial strain and the pathology. This review helps to understand the role of probiotics in allergy and eczema, highlighting their role in the prevention and treatment of the aforementioned diseases.
AB - Atopic disease and eczema are heterogeneous disorders resulting from complex multifactorial interactions. Several studies highlighted the role of gut mucosa in protecting the host from pathogens, regulating the tolerance to them; so a gut weaken barrier may lead to an aberrant immune response and to the release of proinflammatory cytokines, which compromise, in turn, the barrier functionality. A link between allergy and eczema onset and the gut microbiota composition exist, and in particular, it is evident that some microorganisms are able to influence the immune response. For this reason, there is great interest in the beneficial role of probiotics in preventing and treating allergies and eczema. The probiotic benefits depend on many factors, such as the bacterial strain and the pathology. This review helps to understand the role of probiotics in allergy and eczema, highlighting their role in the prevention and treatment of the aforementioned diseases.
KW - Allergy
KW - Gut
KW - Probiotics
KW - Th1
KW - Th2
UR - http://www.scopus.com/inward/record.url?scp=84967221950&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84967221950&partnerID=8YFLogxK
U2 - 10.1016/B978-0-12-802189-7.00064-2
DO - 10.1016/B978-0-12-802189-7.00064-2
M3 - Chapter
SN - 9780128023716
SN - 9780128021897
SP - 831
EP - 837
BT - Probiotics, Prebiotics, and Synbiotics: Bioactive Foods in Health Promotion
PB - Elsevier Inc.
ER -