Probiotics, Prebiotics & Food allergy Prevention: Clinical Data in Children

Alessandro Fiocchi, Valentina Pecora, Lamia Antanios Dahdah

Research output: Contribution to journalArticle

Abstract

PURPOSE OF REVIEW: there are accruing evidences on the role of the intestinal microbiota in the development of allergic diseases among infants. Elaborating on this theoretical basis, studies did assess the possibilities to prevent allergic diseases in infancy through manipulation of the intestinal microbiota. We review here such studies.

RECENT FINDINGS: interventional studies led to conflicting conclusions on the possible role of probiotics and prebiotics in allergy prevention. Two metanalyses published in 2015 did reconcile all data. Guidelines have been predicated on such studies using the GRADE methodology.

SUMMARY: the guidelines for allergy prevention suggest for the first time the use of probiotics and prebiotics. The existing evidences stand for a use of such supplementation in particular for the prevention of eczema. As there is no evidence so far of superiority of one probiotic strand over the others, they should be considered as class and not as individual products.

Original languageEnglish
Pages (from-to)S14-7
JournalJournal of Pediatric Gastroenterology and Nutrition
Volume63 Suppl 1
DOIs
Publication statusPublished - Jul 2016

Fingerprint

Prebiotics
Food Hypersensitivity
Probiotics
Hypersensitivity
Guidelines
Eczema
Theoretical Models
Gastrointestinal Microbiome

Keywords

  • Journal Article

Cite this

Probiotics, Prebiotics & Food allergy Prevention : Clinical Data in Children. / Fiocchi, Alessandro; Pecora, Valentina; Dahdah, Lamia Antanios.

In: Journal of Pediatric Gastroenterology and Nutrition, Vol. 63 Suppl 1, 07.2016, p. S14-7.

Research output: Contribution to journalArticle

@article{ec2f5d240efa45b5888e050c27b47d04,
title = "Probiotics, Prebiotics & Food allergy Prevention: Clinical Data in Children",
abstract = "PURPOSE OF REVIEW: there are accruing evidences on the role of the intestinal microbiota in the development of allergic diseases among infants. Elaborating on this theoretical basis, studies did assess the possibilities to prevent allergic diseases in infancy through manipulation of the intestinal microbiota. We review here such studies.RECENT FINDINGS: interventional studies led to conflicting conclusions on the possible role of probiotics and prebiotics in allergy prevention. Two metanalyses published in 2015 did reconcile all data. Guidelines have been predicated on such studies using the GRADE methodology.SUMMARY: the guidelines for allergy prevention suggest for the first time the use of probiotics and prebiotics. The existing evidences stand for a use of such supplementation in particular for the prevention of eczema. As there is no evidence so far of superiority of one probiotic strand over the others, they should be considered as class and not as individual products.",
keywords = "Journal Article",
author = "Alessandro Fiocchi and Valentina Pecora and Dahdah, {Lamia Antanios}",
year = "2016",
month = "7",
doi = "10.1097/MPG.0000000000001220",
language = "English",
volume = "63 Suppl 1",
pages = "S14--7",
journal = "Journal of Pediatric Gastroenterology and Nutrition",
issn = "0277-2116",
publisher = "Lippincott Williams and Wilkins",

}

TY - JOUR

T1 - Probiotics, Prebiotics & Food allergy Prevention

T2 - Clinical Data in Children

AU - Fiocchi, Alessandro

AU - Pecora, Valentina

AU - Dahdah, Lamia Antanios

PY - 2016/7

Y1 - 2016/7

N2 - PURPOSE OF REVIEW: there are accruing evidences on the role of the intestinal microbiota in the development of allergic diseases among infants. Elaborating on this theoretical basis, studies did assess the possibilities to prevent allergic diseases in infancy through manipulation of the intestinal microbiota. We review here such studies.RECENT FINDINGS: interventional studies led to conflicting conclusions on the possible role of probiotics and prebiotics in allergy prevention. Two metanalyses published in 2015 did reconcile all data. Guidelines have been predicated on such studies using the GRADE methodology.SUMMARY: the guidelines for allergy prevention suggest for the first time the use of probiotics and prebiotics. The existing evidences stand for a use of such supplementation in particular for the prevention of eczema. As there is no evidence so far of superiority of one probiotic strand over the others, they should be considered as class and not as individual products.

AB - PURPOSE OF REVIEW: there are accruing evidences on the role of the intestinal microbiota in the development of allergic diseases among infants. Elaborating on this theoretical basis, studies did assess the possibilities to prevent allergic diseases in infancy through manipulation of the intestinal microbiota. We review here such studies.RECENT FINDINGS: interventional studies led to conflicting conclusions on the possible role of probiotics and prebiotics in allergy prevention. Two metanalyses published in 2015 did reconcile all data. Guidelines have been predicated on such studies using the GRADE methodology.SUMMARY: the guidelines for allergy prevention suggest for the first time the use of probiotics and prebiotics. The existing evidences stand for a use of such supplementation in particular for the prevention of eczema. As there is no evidence so far of superiority of one probiotic strand over the others, they should be considered as class and not as individual products.

KW - Journal Article

U2 - 10.1097/MPG.0000000000001220

DO - 10.1097/MPG.0000000000001220

M3 - Article

C2 - 27380592

VL - 63 Suppl 1

SP - S14-7

JO - Journal of Pediatric Gastroenterology and Nutrition

JF - Journal of Pediatric Gastroenterology and Nutrition

SN - 0277-2116

ER -