Procalcitonin as a useful marker of infection in hemato-oncological patients with fever

Maria T. Sandri; Rita Passerini; Maria E. Leon; Fedro A. Peccatori; Laura Zorzino; Michela Salvatici; Daniela Riggio; Cristina Cassatella; Saverio Cinieri; Giovanni Martinelli

Procalcitonin as a useful marker of infection in hemato-oncological patients with fever

Maria T. Sandri, Rita Passerini, Maria E. Leon, Fedro A. Peccatori, Laura Zorzino, Michela Salvatici, Daniela Riggio, Cristina Cassatella, Saverio Cinieri, Giovanni Martinelli

Research output: Contribution to journal › Article › peer-review

Abstract

Background: The diagnostic utility of procalcitonin (PCT) and C-reactive protein (CRP) to discriminate between infective fever and fever due to inflammation was assessed in hemato-oncological patients treated with aggressive chemotherapy. Patients and Methods: Values of PCT and PCR measured on days -1, 0, 1, 3 and 5 of onset of fever were analyzed using longitudinal regression analysis. Of 236 febrile episodes in 166 patients, 39 were due to bacteremia, 62 to other infections and 135 were classified as fever of unknown origin. Results: PCT concentration increased early only in bacteremia and other infections (p

Original language	English
Pages (from-to)	3061-3065
Number of pages	5
Journal	Anticancer Research
Volume	28
Issue number	5 B
Publication status	Published - Sep 2008

Keywords

C-reactive protein
Infection
Leukopenia
Procalcitonin

ASJC Scopus subject areas

Cancer Research
Oncology

Cite this

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title = "Procalcitonin as a useful marker of infection in hemato-oncological patients with fever",

abstract = "Background: The diagnostic utility of procalcitonin (PCT) and C-reactive protein (CRP) to discriminate between infective fever and fever due to inflammation was assessed in hemato-oncological patients treated with aggressive chemotherapy. Patients and Methods: Values of PCT and PCR measured on days -1, 0, 1, 3 and 5 of onset of fever were analyzed using longitudinal regression analysis. Of 236 febrile episodes in 166 patients, 39 were due to bacteremia, 62 to other infections and 135 were classified as fever of unknown origin. Results: PCT concentration increased early only in bacteremia and other infections (p",

keywords = "C-reactive protein, Infection, Leukopenia, Procalcitonin",

author = "Sandri, {Maria T.} and Rita Passerini and Leon, {Maria E.} and Peccatori, {Fedro A.} and Laura Zorzino and Michela Salvatici and Daniela Riggio and Cristina Cassatella and Saverio Cinieri and Giovanni Martinelli",

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TY - JOUR

T1 - Procalcitonin as a useful marker of infection in hemato-oncological patients with fever

AU - Sandri, Maria T.

AU - Passerini, Rita

AU - Leon, Maria E.

AU - Peccatori, Fedro A.

AU - Zorzino, Laura

AU - Salvatici, Michela

AU - Riggio, Daniela

AU - Cassatella, Cristina

AU - Cinieri, Saverio

AU - Martinelli, Giovanni

PY - 2008/9

Y1 - 2008/9

N2 - Background: The diagnostic utility of procalcitonin (PCT) and C-reactive protein (CRP) to discriminate between infective fever and fever due to inflammation was assessed in hemato-oncological patients treated with aggressive chemotherapy. Patients and Methods: Values of PCT and PCR measured on days -1, 0, 1, 3 and 5 of onset of fever were analyzed using longitudinal regression analysis. Of 236 febrile episodes in 166 patients, 39 were due to bacteremia, 62 to other infections and 135 were classified as fever of unknown origin. Results: PCT concentration increased early only in bacteremia and other infections (p

AB - Background: The diagnostic utility of procalcitonin (PCT) and C-reactive protein (CRP) to discriminate between infective fever and fever due to inflammation was assessed in hemato-oncological patients treated with aggressive chemotherapy. Patients and Methods: Values of PCT and PCR measured on days -1, 0, 1, 3 and 5 of onset of fever were analyzed using longitudinal regression analysis. Of 236 febrile episodes in 166 patients, 39 were due to bacteremia, 62 to other infections and 135 were classified as fever of unknown origin. Results: PCT concentration increased early only in bacteremia and other infections (p

KW - C-reactive protein

KW - Infection

KW - Leukopenia

KW - Procalcitonin

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Procalcitonin as a useful marker of infection in hemato-oncological patients with fever

Abstract

Keywords

ASJC Scopus subject areas

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