Processing of limb kinematics in the interpositus nucleus

Antonino Casabona, Gianfranco Bosco, Vincenzo Perciavalle, Maria Stella Valle

Research output: Contribution to journalArticle

Abstract

Neural representations of limb movement kinematic parameters are common among central nervous system structures involved in motor control, such as the interpositus nucleus of the cerebellum. Much experimental evidence indicates that neurons in the interpositus may encode limb kinematic parameters both during active, voluntary actions and during limb motion imposed passively, which entrains only sensory afferents. With respect to the sensory processing of information related to movement kinematics, we show that interpositus neuronal activity can parse out the directional from the scalar component (i.e., the movement speed) of the velocity vector. Moreover, a differential role for the anterior and posterior portion of interpositus in encoding these parameters emerged from these data, since the activity of the posterior interpositus was specifically associated to changes of movement speed. Limb movement representations in the interpositus nucleus may be instrumental for the control of goal-directed movements such as shaping hand during grasping or precise foot placement during gait. Finally, we discuss the idea that sensory information about the movement kinematics contribute to both feedback and anticipatory processes for limb movement control.

Original languageEnglish
Pages (from-to)103-110
Number of pages8
JournalCerebellum
Volume9
Issue number1
DOIs
Publication statusPublished - Mar 2010

Keywords

  • Interpositus nucleus
  • Limb
  • Movement kinematics

ASJC Scopus subject areas

  • Clinical Neurology
  • Neurology

Fingerprint Dive into the research topics of 'Processing of limb kinematics in the interpositus nucleus'. Together they form a unique fingerprint.

  • Cite this

    Casabona, A., Bosco, G., Perciavalle, V., & Valle, M. S. (2010). Processing of limb kinematics in the interpositus nucleus. Cerebellum, 9(1), 103-110. https://doi.org/10.1007/s12311-009-0149-x