Production of serum-opacity factor by Streptococcus pyogenes strains isolated from pharyngitis in children prevalence of ≪rheumatogenic≫ M types among of-negative strains

A. M. Molina, G. Coratza, R. A. Musmanno, N. Figura, G. M. Rossolini

Research output: Contribution to journalArticlepeer-review

Abstract

Two hundred ten S. pyogenes strains isolated in 1979, 1980 and 1984 from children with pharyngitis were here examined for properties which might be relevant to their rheumatogenic potential. Strains were first tested for the production of streptococcal serum-opacity factor and, among those scored as OF-negative, the presence was then verified of M types which have been epidemiologically related to rheumatic fever. Members of ≪rheumatogenic≫ M types are present among strains causing pharyngitis in children; which, however, also include a considerable proportion of OF-positive, probably non-rheumatogenic, strains. The results are discussed in the light of the low incidence of rheumatic fever in this country.

Original languageEnglish
Pages (from-to)37-41
Number of pages5
JournalEuropean Journal of Epidemiology
Volume1
Issue number1
DOIs
Publication statusPublished - Mar 1985

Keywords

  • Rheumatogenic M types
  • S. pyogenes M types
  • S. pyogenes serum-opacity factor

ASJC Scopus subject areas

  • Epidemiology

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