Prognosis of asymptomatic patients with hypertrophic cardiomyopathy and nonsustained ventricular tachycardia

P. Spirito, C. Rapezzi, C. Autore, P. Bruzzi, P. Bellone, P. Ortolani, P. V. Fragola, F. Chiarella, M. Zoni-Berisso, A. Branzi, D. Cannata, B. Magnani, C. Vecchio

Research output: Contribution to journalArticlepeer-review


Background: In the early 1980s, studies performed in highly selected referral patients with hypertrophic cardiomyopathy reported a strong association between the presence of brief episodes of ventricular tachycardia (VT) on ambulatory ECG monitoring and sudden death. These observations led to antiarrhythmic treatment in many patients with hypertrophic cardiomyopathy and brief episodes of VT. In recent years, however, a growing awareness of the potential arrhythmogenic effects of antiarrhythmic medications has raised doubts regarding such a therapeutic approach, particularly in less selected and lower-risk patient populations. Methods and Results: In the present study, we examined the prognostic significance of nonsustained VT in a population of 151 patients with hypertrophic cardiomyopathy who were asymptomatic or had only mild symptoms at the time of their initial ambulatory ECG recording. Of the 151 study patients, 42 had episodes of VT and 109 did not. The runs of VT ranged from 3 to 19 beats, with 35 patients (83%) having

Original languageEnglish
Pages (from-to)2743-2747
Number of pages5
Issue number6
Publication statusPublished - 1994


  • cardiomyopathy
  • death, sudden
  • hypertrophy
  • tachycardia

ASJC Scopus subject areas

  • Physiology
  • Cardiology and Cardiovascular Medicine

Fingerprint Dive into the research topics of 'Prognosis of asymptomatic patients with hypertrophic cardiomyopathy and nonsustained ventricular tachycardia'. Together they form a unique fingerprint.

Cite this