Purpose: This study analyses the clinical and prognostic features of 56 patients (pts) with nocturnal frontal lobe epilepsy (NFLE) after a long follow-up. Methods: We selected 56 patients with NFLE according to the following criteria: a history of nocturnal motor seizures suggesting frontal lobe involvement, video-PSG recording of at least 1 major episode or 2 stereotyped paroxysmal arousals, a follow-up period > 5 years, last visit within the last 24 months. On the basis of seizure frequency at the last visit our population was divided into 2 groups: pts with Negative Evolution (NE- seizure frequency varying from daily to pluri-yearly: 31 pts, 55.4%) and pts with Positive Evolution (PE- seizure-free for at least 1 year or with sporadic seizure: 25 pts, 44.6%). Results: Among NE pts the mean age at onset of epilepsy was slightly lower than in PE pts (PE 17.8 years vs NE 11.8 years; p = 0.046); a family history of febrile convulsions (FC) was found only in the PE group (16%). No significant differences were observed between the two groups about the others variables analyzed. Conclusions: These preliminary data show only two significant differences between NE and PE pts regarding earlier age at onset in the NE group, that seems to be a negative prognostic factor, and a positive family history for FC reported only in the PE group.
|Translated title of the contribution||Prognosis of nocturnal frontal lobe epilepsy: Study of long follow-up period in 56 patients|
|Number of pages||2|
|Journal||Bollettino - Lega Italiana contro l'Epilessia|
|Publication status||Published - May 2008|
ASJC Scopus subject areas
- Clinical Neurology