Prognostic and electroclinical features of grand mai epilepsies

Roberto D’Alessandro, P. Pazzaglia, P. Tinuper, R. Ferrara, R. Fabbri, E. Lugaresi

Research output: Contribution to journalArticlepeer-review


We studied the electroclinical features and prognosis of 103 patients with tonic-clonic sci/urcs alone. Patients were classified into three groups according lo seizure semiology and imerictal EEG: primary grand mal. focal grand mal and indeterminate grand mal. Discriminant analysis showed that a number of other electroclinical features had no significant classiilcatory power. Patients have been followed for 2-10 years. At the last observation 40% of patients were free from tonic-clonic seizures and 23% had fewer than 1 seizure a year, without differences among the three groups. The appearance of ‘minor’ (absence or partial) seizures during follow-up occurred in 12 patients and did not change the prognosis of tonic-clonic seizures. At the end of follow-up. 96% of patients had a normal social adjustment. Grand mal epilepsies therefore appear to have a good prognosis.

Original languageEnglish
Pages (from-to)339-345
Number of pages7
JournalEuropean Neurology
Issue number5
Publication statusPublished - 1986


  • Electroclinical features
  • Grand mal epilepsies
  • Prognosis

ASJC Scopus subject areas

  • Clinical Neurology
  • Neurology


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