Prognostic characteristics of cardiopulmonary exercise testing in caucasian and African American patients with heart failure

Ross Arena, Jonathan Myers, Joshua Abella, Mary Ann Peberdy, Daniel Bensimhon, Paul Chase, Marco Guazzi

Research output: Contribution to journalArticlepeer-review

Abstract

Peak oxygen consumption (VO2) and ventilatory efficiency (minute ventilation/carbon dioxide output [VE/VCO2] slope) are prognostically important in heart failure (HF). The purpose of the present study was to compare the prognostic characteristics of these variables between Caucasian and African American patients. A total of 662 HF patients (455 Caucasian/207 African American) underwent cardiopulmonary exercise testing and were tracked for major cardiac events. The VE/VCO2 slope was the strongest prognostic marker (chi-square ≥18.9, P2 was a significant univariate predictor in both Caucasian (chi-square 42.0, P2 in the African American subgroup was due to its lack of prognostic significance in female patients. While the VE/VCO2 slope was the most robust prognostic marker in both Caucasian and African American patients, the predictive ability of peak VO2 seems to be influenced by race and sex.

Original languageEnglish
Pages (from-to)310-315
Number of pages6
JournalCongestive Heart Failure
Volume14
Issue number6
DOIs
Publication statusPublished - Nov 2008

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Emergency Medicine
  • Emergency

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