Prognostic factors for benefits from percutaneous transhepatic biliary drainage

M. C. Castoldi, P. Pisani, G. Ideol, M. Bellomi, G. Cozzi, M. A. Pestalozza, A. Severini

Research output: Contribution to journalArticlepeer-review

Abstract

The authors reviewed the clinical records and radiographs of 87 patients with neoplastic biliary obstruction who were treated by percutaneous transhepatic biliary drainage (PTBD). Multivariate analysis was used to identify factors predicting survival beyond 30 or 60 days. The significant parameters associated with survival beyond 30 days are low serum indirect bilirubin and blood urea nitrogen (BUN) levels; apyrexia prior to drainage; small tumour mass causing obstruction; the involvement of hepatic parenchyma and abdominal spread. The significant parameters associated with survival beyond 60 days are serum cholinesterase and a smaller volume of disease. Neither the histology nor the site of the tumour, nor the other biochemical indices considered are significantly related to the survival of the patients. Pre-PTBD radiological and laboratory data can differentiate a group of patients likely to benefit from biliary drainage from those for whom the procedure will neither improve well-being nor survival.

Original languageEnglish
Pages (from-to)119-122
Number of pages4
JournalJournal of Interventional Radiology
Volume6
Issue number4
Publication statusPublished - Dec 1991

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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