Prognostic factors for patients with chronic myeloid leukaemia in chronic phase treated with imatinib mesylate after failure of interferon alfa

D. Marin; S. Marktel; M. Bua; R. M. Szydlo; A. Franceschino; I. Nathan; I. Foot; C. Crawley; T. Nakorn Nakorn; E. Olavarria; A. Lennard; A. Neylon; S. G. O'Brien; J. M. Goldman; J. F. Apperley

doi:10.1038/sj.leu.2402996

Prognostic factors for patients with chronic myeloid leukaemia in chronic phase treated with imatinib mesylate after failure of interferon alfa

D. Marin, S. Marktel, M. Bua, R. M. Szydlo, A. Franceschino, I. Nathan, I. Foot, C. Crawley, T. Nakorn Nakorn, E. Olavarria, A. Lennard, A. Neylon, S. G. O'Brien, J. M. Goldman, J. F. Apperley

IRCCS Ospedale San Raffaele

Research output: Contribution to journal › Article › peer-review

Abstract

We assessed clinical results in 145 patients with chronic myeloid leukaemia in chronic phase who satisfied criteria for interferon-α failure and were thus eligible for treatment with imatinib at the Hammersmith Hospital. We used univariate and multivariate analyses to develop a risk score based on features defined after treatment for 3 months. We identified a low neutrophil count and poor cytogenetic response (

Original language	English
Pages (from-to)	1448-1453
Number of pages	6
Journal	Leukemia
Volume	17
Issue number	8
DOIs	https://doi.org/10.1038/sj.leu.2402996
Publication status	Published - Aug 1 2003

Keywords

Chronic myeloid leukaemia
Cytogenetic response
Imatinib mesylate
Neutropenia
Prognostic factors

ASJC Scopus subject areas

Hematology
Cancer Research

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10.1038/sj.leu.2402996

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Marin, D., Marktel, S., Bua, M., Szydlo, R. M., Franceschino, A., Nathan, I., Foot, I., Crawley, C., Nakorn, T. N., Olavarria, E., Lennard, A., Neylon, A., O'Brien, S. G., Goldman, J. M., & Apperley, J. F. (2003). Prognostic factors for patients with chronic myeloid leukaemia in chronic phase treated with imatinib mesylate after failure of interferon alfa. Leukemia, 17(8), 1448-1453. https://doi.org/10.1038/sj.leu.2402996

Prognostic factors for patients with chronic myeloid leukaemia in chronic phase treated with imatinib mesylate after failure of interferon alfa. / Marin, D.; Marktel, S.; Bua, M.; Szydlo, R. M.; Franceschino, A.; Nathan, I.; Foot, I.; Crawley, C.; Nakorn, T. Nakorn; Olavarria, E.; Lennard, A.; Neylon, A.; O'Brien, S. G.; Goldman, J. M.; Apperley, J. F.

In: Leukemia, Vol. 17, No. 8, 01.08.2003, p. 1448-1453.

Research output: Contribution to journal › Article › peer-review

Marin, D, Marktel, S, Bua, M, Szydlo, RM, Franceschino, A, Nathan, I, Foot, I, Crawley, C, Nakorn, TN, Olavarria, E, Lennard, A, Neylon, A, O'Brien, SG, Goldman, JM & Apperley, JF 2003, 'Prognostic factors for patients with chronic myeloid leukaemia in chronic phase treated with imatinib mesylate after failure of interferon alfa', Leukemia, vol. 17, no. 8, pp. 1448-1453. https://doi.org/10.1038/sj.leu.2402996

Marin, D. ; Marktel, S. ; Bua, M. ; Szydlo, R. M. ; Franceschino, A. ; Nathan, I. ; Foot, I. ; Crawley, C. ; Nakorn, T. Nakorn ; Olavarria, E. ; Lennard, A. ; Neylon, A. ; O'Brien, S. G. ; Goldman, J. M. ; Apperley, J. F. / Prognostic factors for patients with chronic myeloid leukaemia in chronic phase treated with imatinib mesylate after failure of interferon alfa. In: Leukemia. 2003 ; Vol. 17, No. 8. pp. 1448-1453.

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Prognostic factors for patients with chronic myeloid leukaemia in chronic phase treated with imatinib mesylate after failure of interferon alfa

Abstract

Keywords

ASJC Scopus subject areas

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