Prognostic factors in chronic subdural hematoma: results from a monocentric consecutive surgical series of 605 patients

Susanna Bacigaluppi, Fedra Guastalli, Nicola L. Bragazzi, Alberto Balestrino, Paolo Bruzzi, Gianluigi Zona

Research output: Contribution to journalArticlepeer-review


BACKGROUND: The study of age-related diseases like chronic subdural hematoma (CSDH) is of high interest, considered the general ageing of the population. This investigation aimed to identify the main clinical characteristics of CSDH patients, to evaluate the impact of the disease on quality of life, its treatment and comorbidities/complications and to compare our data with other surgical series published over the past 5 years. METHODS: A retrospective cohort study including all consecutive patients operated for CSDH between January 1, 2006 and December 31, 2013 at the Unit of Neurosurgery of our hospital was carried out. RESULTS: 605 patients were included in the study (66.0% male, mean age 77.5±10.5 years). History of brain trauma was reported in 65.6%. Common comorbidities were hypertension (59.0%), cardiopathies (36.0%), and previous stroke (23.6%). Clotting and coagulation alterations were present in 27.2% and 17.0%, respectively. In 24.0% of cases, the hematoma was bilateral. 17.3% had more than one surgery. Length of stay was of 14.8±10.1 days. Baseline Karnofsky Performance Score (KPS), presurgical KPS, and KPS at discharge were 87.7±14.9, 64.9 ±19.8 and 76.7±27.2, respectively. A complete recovery was observed in 62.9% of patients. Mortality rate during hospitalization was 7.4%. CONCLUSIONS: The knowledge of clinical and surgical factors which might impact on the clinical outcomes could help to better manage patients with CSDH, which represents a surgically "simple" but, indeed, not trivial disease.

Original languageEnglish
Pages (from-to)14-23
Number of pages10
JournalJournal of Neurosurgical Sciences
Issue number1
Publication statusPublished - Feb 1 2021

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology


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