Abstract
This report presents a retrospective prognostic study of 65 patients with intramedullary astrocytoma surgically treated between 1953 and 1990. Median survival and statistical survival at 5 years were assessed in relation to clinical, histological and therapeutic factors for each patient. Results showed that factors positively influencing the prognosis are low histological grade of the tumour and good pre- and post-operative general conditions. Among the grade II astrocytomas, the fibrillary and protoplasmatic types presented longer survival times regardless of the type of removal performed. In anaplastic astrocytomas the simultaneous presence of certain morphological features indicative of higher malignancy negatively influenced survival. The degree of resection did not influence average survival within each histological grade.
| Original language | English |
|---|---|
| Pages (from-to) | 1-5 |
| Number of pages | 5 |
| Journal | Clinical Neurology and Neurosurgery |
| Volume | 99 |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - Feb 1997 |
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Keywords
- Intramedullary astrocytoma
- Prognostic factor
- Surgery
ASJC Scopus subject areas
- Clinical Neurology
- Surgery
- Neurology
Cite this
Prognostic factors in intramedullary astrocytomas. / Innocenzi, Gualtiero; Salvati, Maurizio; Cervoni, Luigi; Delfini, Roberto; Cantore, Giampaolo.
In: Clinical Neurology and Neurosurgery, Vol. 99, No. 1, 02.1997, p. 1-5.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Prognostic factors in intramedullary astrocytomas
AU - Innocenzi, Gualtiero
AU - Salvati, Maurizio
AU - Cervoni, Luigi
AU - Delfini, Roberto
AU - Cantore, Giampaolo
PY - 1997/2
Y1 - 1997/2
N2 - This report presents a retrospective prognostic study of 65 patients with intramedullary astrocytoma surgically treated between 1953 and 1990. Median survival and statistical survival at 5 years were assessed in relation to clinical, histological and therapeutic factors for each patient. Results showed that factors positively influencing the prognosis are low histological grade of the tumour and good pre- and post-operative general conditions. Among the grade II astrocytomas, the fibrillary and protoplasmatic types presented longer survival times regardless of the type of removal performed. In anaplastic astrocytomas the simultaneous presence of certain morphological features indicative of higher malignancy negatively influenced survival. The degree of resection did not influence average survival within each histological grade.
AB - This report presents a retrospective prognostic study of 65 patients with intramedullary astrocytoma surgically treated between 1953 and 1990. Median survival and statistical survival at 5 years were assessed in relation to clinical, histological and therapeutic factors for each patient. Results showed that factors positively influencing the prognosis are low histological grade of the tumour and good pre- and post-operative general conditions. Among the grade II astrocytomas, the fibrillary and protoplasmatic types presented longer survival times regardless of the type of removal performed. In anaplastic astrocytomas the simultaneous presence of certain morphological features indicative of higher malignancy negatively influenced survival. The degree of resection did not influence average survival within each histological grade.
KW - Intramedullary astrocytoma
KW - Prognostic factor
KW - Surgery
UR - http://www.scopus.com/inward/record.url?scp=0030975285&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0030975285&partnerID=8YFLogxK
U2 - 10.1016/S0303-8467(96)00555-0
DO - 10.1016/S0303-8467(96)00555-0
M3 - Article
VL - 99
SP - 1
EP - 5
JO - Clinical Neurology and Neurosurgery
JF - Clinical Neurology and Neurosurgery
SN - 0303-8467
IS - 1
ER -