Prognostic factors in intramedullary astrocytomas

Gualtiero Innocenzi, Maurizio Salvati, Luigi Cervoni, Roberto Delfini, Giampaolo Cantore

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Abstract

This report presents a retrospective prognostic study of 65 patients with intramedullary astrocytoma surgically treated between 1953 and 1990. Median survival and statistical survival at 5 years were assessed in relation to clinical, histological and therapeutic factors for each patient. Results showed that factors positively influencing the prognosis are low histological grade of the tumour and good pre- and post-operative general conditions. Among the grade II astrocytomas, the fibrillary and protoplasmatic types presented longer survival times regardless of the type of removal performed. In anaplastic astrocytomas the simultaneous presence of certain morphological features indicative of higher malignancy negatively influenced survival. The degree of resection did not influence average survival within each histological grade.

Original languageEnglish
Pages (from-to)1-5
Number of pages5
JournalClinical Neurology and Neurosurgery
Volume99
Issue number1
DOIs
Publication statusPublished - Feb 1997

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Keywords

  • Intramedullary astrocytoma
  • Prognostic factor
  • Surgery

ASJC Scopus subject areas

  • Clinical Neurology
  • Surgery
  • Neurology

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