I FATTORI INDICATIVI DI RICADUTA ALLA SOSPENSIONE DELLA TERAPIA NEI PAZIENTI CON EPILESSIE PARZIALI

Translated title of the contribution: Prognostic factors of relapse in controlled patients with partial epilepsy

G. Procaccianti, P. Tinuper, P. Avoni, F. Provini, E. Lugaresi, A. Baruzzi

Research output: Contribution to journalArticle

Abstract

Since 1980 we have adopted a standard protocol for therapy withdrawal in epileptic patients seizure-free for 2-6 years: here are presented the preliminary data on 87 patients with partial epilepsy, followed during the withdrawal period (9 months) and 3 years after suspension or relapse. The series included 24 males and 18 females aged 8-60 years; 20 had complex partial -CP- seizures (11 with sporadic secondary generalization -PGS-), 5 had simple partial -SP- seizures (4 with PSG), 12 had only PSG. Twenty-six patients (70%) relapsed; of these 13 had CP, 5 SP and 8 PSG. Unfavourable factors were: known etiology (perinatal asphyxia, head trauma, meningitis and febrile convulsions), seizure onset after 15 years of age, epileptiform paroxysms at the start of, or during follow-up. The longer it took to control seizures, the higher the rate of relapse, although early therapy did not have a favourable influence on the outcome.

Original languageItalian
Pages (from-to)75-76
Number of pages2
JournalBollettino - Lega Italiana contro l'Epilessia
Issue number70-71
Publication statusPublished - 1990

Fingerprint

Partial Epilepsy
Recurrence
Seizures
Febrile Seizures
Asphyxia
Secondary Prevention
Craniocerebral Trauma
Meningitis
Epilepsy
Suspensions
Therapeutics

ASJC Scopus subject areas

  • Clinical Neurology

Cite this

@article{50639c2a22ca42c2879eee916a8db6ef,
title = "I FATTORI INDICATIVI DI RICADUTA ALLA SOSPENSIONE DELLA TERAPIA NEI PAZIENTI CON EPILESSIE PARZIALI",
abstract = "Since 1980 we have adopted a standard protocol for therapy withdrawal in epileptic patients seizure-free for 2-6 years: here are presented the preliminary data on 87 patients with partial epilepsy, followed during the withdrawal period (9 months) and 3 years after suspension or relapse. The series included 24 males and 18 females aged 8-60 years; 20 had complex partial -CP- seizures (11 with sporadic secondary generalization -PGS-), 5 had simple partial -SP- seizures (4 with PSG), 12 had only PSG. Twenty-six patients (70{\%}) relapsed; of these 13 had CP, 5 SP and 8 PSG. Unfavourable factors were: known etiology (perinatal asphyxia, head trauma, meningitis and febrile convulsions), seizure onset after 15 years of age, epileptiform paroxysms at the start of, or during follow-up. The longer it took to control seizures, the higher the rate of relapse, although early therapy did not have a favourable influence on the outcome.",
author = "G. Procaccianti and P. Tinuper and P. Avoni and F. Provini and E. Lugaresi and A. Baruzzi",
year = "1990",
language = "Italian",
pages = "75--76",
journal = "Bollettino - Lega Italiana contro l'Epilessia",
issn = "0394-560X",
publisher = "Lega Italiana contro l'Epilessia",
number = "70-71",

}

TY - JOUR

T1 - I FATTORI INDICATIVI DI RICADUTA ALLA SOSPENSIONE DELLA TERAPIA NEI PAZIENTI CON EPILESSIE PARZIALI

AU - Procaccianti, G.

AU - Tinuper, P.

AU - Avoni, P.

AU - Provini, F.

AU - Lugaresi, E.

AU - Baruzzi, A.

PY - 1990

Y1 - 1990

N2 - Since 1980 we have adopted a standard protocol for therapy withdrawal in epileptic patients seizure-free for 2-6 years: here are presented the preliminary data on 87 patients with partial epilepsy, followed during the withdrawal period (9 months) and 3 years after suspension or relapse. The series included 24 males and 18 females aged 8-60 years; 20 had complex partial -CP- seizures (11 with sporadic secondary generalization -PGS-), 5 had simple partial -SP- seizures (4 with PSG), 12 had only PSG. Twenty-six patients (70%) relapsed; of these 13 had CP, 5 SP and 8 PSG. Unfavourable factors were: known etiology (perinatal asphyxia, head trauma, meningitis and febrile convulsions), seizure onset after 15 years of age, epileptiform paroxysms at the start of, or during follow-up. The longer it took to control seizures, the higher the rate of relapse, although early therapy did not have a favourable influence on the outcome.

AB - Since 1980 we have adopted a standard protocol for therapy withdrawal in epileptic patients seizure-free for 2-6 years: here are presented the preliminary data on 87 patients with partial epilepsy, followed during the withdrawal period (9 months) and 3 years after suspension or relapse. The series included 24 males and 18 females aged 8-60 years; 20 had complex partial -CP- seizures (11 with sporadic secondary generalization -PGS-), 5 had simple partial -SP- seizures (4 with PSG), 12 had only PSG. Twenty-six patients (70%) relapsed; of these 13 had CP, 5 SP and 8 PSG. Unfavourable factors were: known etiology (perinatal asphyxia, head trauma, meningitis and febrile convulsions), seizure onset after 15 years of age, epileptiform paroxysms at the start of, or during follow-up. The longer it took to control seizures, the higher the rate of relapse, although early therapy did not have a favourable influence on the outcome.

UR - http://www.scopus.com/inward/record.url?scp=0025205208&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0025205208&partnerID=8YFLogxK

M3 - Articolo

AN - SCOPUS:0025205208

SP - 75

EP - 76

JO - Bollettino - Lega Italiana contro l'Epilessia

JF - Bollettino - Lega Italiana contro l'Epilessia

SN - 0394-560X

IS - 70-71

ER -