- Acute decompensated heart failure
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Prognostic impact of comorbidities in hospitalized patients with acute exacerbation of chronic heart failure. / Scrutinio, D.; Passantino, A.; Guida, P.; Ammirati, E.; Oliva, F.; Braga, S.S.; La Rovere, M.T.; Lagioia, R.; Frigerio, M.In: European Journal of Internal Medicine, Vol. 34, 2016, p. 63-67.
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TY - JOUR
T1 - Prognostic impact of comorbidities in hospitalized patients with acute exacerbation of chronic heart failure
AU - Scrutinio, D.
AU - Passantino, A.
AU - Guida, P.
AU - Ammirati, E.
AU - Oliva, F.
AU - Braga, S.S.
AU - La Rovere, M.T.
AU - Lagioia, R.
AU - Frigerio, M.
N1 - Export Date: 14 March 2017 CODEN: EJIME Correspondence Address: Scrutinio, D.; Fondazione “S. 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PY - 2016
Y1 - 2016
N2 - Background To assess the impact of comorbidities on long-term all-cause mortality in patients hospitalized with exacerbated signs/symptoms of previously chronic stable HF (AE-CHF). Methods 1119 patients admitted for AE-CHF and with NT-proBNP levels > 900 pg/mL were enrolled. Univariable and multivariable Cox analyses were performed to assess the association of age, gender, hypertension, diabetes, obesity, atrial fibrillation, coronary heart disease (CHD), chronic obstructive pulmonary disease, previous cerebrovascular accidents, chronic liver disease (CLD), thyroid disease, renal impairment (RI), and anemia with 3-year all-cause mortality. Results During the follow-up, 441 patients died and 126 underwent heart transplantation (HT) or ventricular assist device (VAD) implantation. 45.8% of the fatal events and 52.4% of HT/VAD implantations occurred within 180 days after admission. Increasing age (p = .012), obesity (p = .037), atrial fibrillation (p = .030), CHD (p = .015), CLD (p = .001), RI (p
AB - Background To assess the impact of comorbidities on long-term all-cause mortality in patients hospitalized with exacerbated signs/symptoms of previously chronic stable HF (AE-CHF). Methods 1119 patients admitted for AE-CHF and with NT-proBNP levels > 900 pg/mL were enrolled. Univariable and multivariable Cox analyses were performed to assess the association of age, gender, hypertension, diabetes, obesity, atrial fibrillation, coronary heart disease (CHD), chronic obstructive pulmonary disease, previous cerebrovascular accidents, chronic liver disease (CLD), thyroid disease, renal impairment (RI), and anemia with 3-year all-cause mortality. Results During the follow-up, 441 patients died and 126 underwent heart transplantation (HT) or ventricular assist device (VAD) implantation. 45.8% of the fatal events and 52.4% of HT/VAD implantations occurred within 180 days after admission. Increasing age (p = .012), obesity (p = .037), atrial fibrillation (p = .030), CHD (p = .015), CLD (p = .001), RI (p
KW - Acute decompensated heart failure
KW - Comorbidity
KW - Mortality
U2 - 10.1016/j.ejim.2016.05.020
DO - 10.1016/j.ejim.2016.05.020
M3 - Article
VL - 34
SP - 63
EP - 67
JO - European Journal of Internal Medicine
JF - European Journal of Internal Medicine
SN - 0953-6205