Prognostic indicators in pediatric clinically isolated syndrome

P. Iaffaldano; M. Simone; G. Lucisano; A. Ghezzi; G. Coniglio; V. Brescia Morra; G. Salemi; F. Patti; A. Lugaresi; G. Izquierdo; R. Bergamaschi; J.A. Cabrera-Gomez; C. Pozzilli; E. Millefiorini; R. Alroughani; C. Boz; E. Pucci; G.B. Zimatore; P. Sola; G. Lus; D. Maimone; C. Avolio; E. Cocco; S.A. Sajedi; G. Costantino; P. Duquette; V. Shaygannejad; T. Petersen; R. Fernández Bolaños; D. Paolicelli; C. Tortorella; T. Spelman; L. Margari; M.P. Amato; G. Comi; H. Butzkueven; M. Trojano; on behalf of the Italian iMedWeb Registry; the MSBase Registry; D. Spitaleri; M.R. Rottoli; B. Ardito; G. Iuliano; E. Montanari; E. Granieri; G. Tedeschi; A. Bertolotto; F. Granella; G. Di Battista; P. Gallo; P. Cavalla; P. Bellantonio; F. De Robertis; L. Durelli; E. Scarpini; M. Rezzonico; A. Protti; C. Solaro; F. Corea; A. Bosco; M. Vianello; M.T. Ferrò; R. Balgera; R. Grasso; G. De Luca; D. Farina; D. Travaglini; M. di Ioia; V. Di Tommaso; L. Mancinelli; E. Pietrolongo; R. Hupperts; M.E. Rio; M. Terzi; M. Barnett; M. Slee; V. Van Pesch; A. Savino; J. Lechner-Scott; P. Grammond; B. Singhal; C. Zwanikken; M. Fiol; L. Patrucco; M. Paine; P. McCombefrom; F. Grand'Maison

doi:10.1002/ana.24938

Prognostic indicators in pediatric clinically isolated syndrome

P. Iaffaldano, M. Simone, G. Lucisano, A. Ghezzi, G. Coniglio, V. Brescia Morra, G. Salemi, F. Patti, A. Lugaresi, G. Izquierdo, R. Bergamaschi, J.A. Cabrera-Gomez, C. Pozzilli, E. Millefiorini, R. Alroughani, C. Boz, E. Pucci, G.B. Zimatore, P. Sola, G. LusD. Maimone, C. Avolio, E. Cocco, S.A. Sajedi, G. Costantino, P. Duquette, V. Shaygannejad, T. Petersen, R. Fernández Bolaños, D. Paolicelli, C. Tortorella, T. Spelman, L. Margari, M.P. Amato, G. Comi, H. Butzkueven, M. Trojano, on behalf of the Italian iMedWeb Registry, the MSBase Registry, D. Spitaleri, M.R. Rottoli, B. Ardito, G. Iuliano, E. Montanari, E. Granieri, G. Tedeschi, A. Bertolotto, F. Granella, G. Di Battista, P. Gallo, P. Cavalla, P. Bellantonio, F. De Robertis, L. Durelli, E. Scarpini, M. Rezzonico, A. Protti, C. Solaro, F. Corea, A. Bosco, M. Vianello, M.T. Ferrò, R. Balgera, R. Grasso, G. De Luca, D. Farina, D. Travaglini, M. di Ioia, V. Di Tommaso, L. Mancinelli, E. Pietrolongo, R. Hupperts, M.E. Rio, M. Terzi, M. Barnett, M. Slee, V. Van Pesch, A. Savino, J. Lechner-Scott, P. Grammond, B. Singhal, C. Zwanikken, M. Fiol, L. Patrucco, M. Paine, P. McCombefrom, F. Grand'Maison

Research output: Contribution to journal › Article › peer-review

Original language	English
Pages (from-to)	729-739
Number of pages	11
Journal	Annals of Neurology
Volume	81
Issue number	5
DOIs	https://doi.org/10.1002/ana.24938
Publication status	Published - 2017

Keywords

azathioprine
beta interferon
glatiramer
immunomodulating agent
immunosuppressive agent
natalizumab, acute disseminated encephalomyelitis
adolescent
Article
brain stem
childhood disease
clinical assessment
clinical indicator
cohort analysis
controlled study
decision tree
demyelinating disease
disability
disease exacerbation
drug exposure
Expanded Disability Status Scale
female
follow up
hazard ratio
human
immunosuppressive treatment
major clinical study
male
multicenter study
multiple sclerosis
observational study
onset age
optic neuritis
pediatric onset multiple sclerosis
priority journal
prognosis
proportional hazards model
prospective study
recursive partitioning and amalgamation tree
regression analysis
relapse
risk factor
risk reduction
spinal cord disease
child
clinical trial
Demyelinating Diseases
diagnostic imaging
disease course
pathophysiology
register
retrospective study, Adolescent
Age of Onset
Child
Disease Progression
Female
Follow-Up Studies
Humans
Male
Multiple Sclerosis
Prognosis
Registries
Retrospective Studies
Risk Factors

Access to Document

10.1002/ana.24938

https://www.scopus.com/inward/record.uri?eid=2-s2.0-85019942050&doi=10.1002%2fana.24938&partnerID=40&md5=add526aad1c1cc9c6b112b10d624dabc

Cite this

Iaffaldano, P., Simone, M., Lucisano, G., Ghezzi, A., Coniglio, G., Brescia Morra, V., Salemi, G., Patti, F., Lugaresi, A., Izquierdo, G., Bergamaschi, R., Cabrera-Gomez, J. A., Pozzilli, C., Millefiorini, E., Alroughani, R., Boz, C., Pucci, E., Zimatore, G. B., Sola, P., ... Grand'Maison, F. (2017). Prognostic indicators in pediatric clinically isolated syndrome. Annals of Neurology, 81(5), 729-739. https://doi.org/10.1002/ana.24938

Prognostic indicators in pediatric clinically isolated syndrome. / Iaffaldano, P.; Simone, M.; Lucisano, G.; Ghezzi, A.; Coniglio, G.; Brescia Morra, V.; Salemi, G.; Patti, F.; Lugaresi, A.; Izquierdo, G.; Bergamaschi, R.; Cabrera-Gomez, J.A.; Pozzilli, C.; Millefiorini, E.; Alroughani, R.; Boz, C.; Pucci, E.; Zimatore, G.B.; Sola, P.; Lus, G.; Maimone, D.; Avolio, C.; Cocco, E.; Sajedi, S.A.; Costantino, G.; Duquette, P.; Shaygannejad, V.; Petersen, T.; Fernández Bolaños, R.; Paolicelli, D.; Tortorella, C.; Spelman, T.; Margari, L.; Amato, M.P.; Comi, G.; Butzkueven, H.; Trojano, M.; Registry, on behalf of the Italian iMedWeb; Registry, the MSBase; Spitaleri, D.; Rottoli, M.R.; Ardito, B.; Iuliano, G.; Montanari, E.; Granieri, E.; Tedeschi, G.; Bertolotto, A.; Granella, F.; Di Battista, G.; Gallo, P.; Cavalla, P.; Bellantonio, P.; De Robertis, F.; Durelli, L.; Scarpini, E.; Rezzonico, M.; Protti, A.; Solaro, C.; Corea, F.; Bosco, A.; Vianello, M.; Ferrò, M.T.; Balgera, R.; Grasso, R.; De Luca, G.; Farina, D.; Travaglini, D.; di Ioia, M.; Di Tommaso, V.; Mancinelli, L.; Pietrolongo, E.; Hupperts, R.; Rio, M.E.; Terzi, M.; Barnett, M.; Slee, M.; Van Pesch, V.; Savino, A.; Lechner-Scott, J.; Grammond, P.; Singhal, B.; Zwanikken, C.; Fiol, M.; Patrucco, L.; Paine, M.; McCombefrom, P.; Grand'Maison, F.

In: Annals of Neurology, Vol. 81, No. 5, 2017, p. 729-739.

Research output: Contribution to journal › Article › peer-review

Iaffaldano, P, Simone, M, Lucisano, G, Ghezzi, A, Coniglio, G, Brescia Morra, V, Salemi, G, Patti, F, Lugaresi, A, Izquierdo, G, Bergamaschi, R, Cabrera-Gomez, JA, Pozzilli, C, Millefiorini, E, Alroughani, R, Boz, C, Pucci, E, Zimatore, GB, Sola, P, Lus, G, Maimone, D, Avolio, C, Cocco, E, Sajedi, SA, Costantino, G, Duquette, P, Shaygannejad, V, Petersen, T, Fernández Bolaños, R, Paolicelli, D, Tortorella, C, Spelman, T, Margari, L, Amato, MP , Comi, G, Butzkueven, H, Trojano, M, Registry, OBOTIIM, Registry, TMSB, Spitaleri, D, Rottoli, MR, Ardito, B, Iuliano, G, Montanari, E, Granieri, E, Tedeschi, G, Bertolotto, A, Granella, F, Di Battista, G, Gallo, P, Cavalla, P, Bellantonio, P, De Robertis, F, Durelli, L, Scarpini, E, Rezzonico, M, Protti, A, Solaro, C, Corea, F, Bosco, A, Vianello, M, Ferrò, MT, Balgera, R, Grasso, R, De Luca, G, Farina, D, Travaglini, D, di Ioia, M, Di Tommaso, V, Mancinelli, L, Pietrolongo, E, Hupperts, R, Rio, ME, Terzi, M, Barnett, M, Slee, M, Van Pesch, V, Savino, A, Lechner-Scott, J, Grammond, P, Singhal, B, Zwanikken, C, Fiol, M, Patrucco, L, Paine, M, McCombefrom, P & Grand'Maison, F 2017, 'Prognostic indicators in pediatric clinically isolated syndrome', Annals of Neurology, vol. 81, no. 5, pp. 729-739. https://doi.org/10.1002/ana.24938

Iaffaldano, P. ; Simone, M. ; Lucisano, G. ; Ghezzi, A. ; Coniglio, G. ; Brescia Morra, V. ; Salemi, G. ; Patti, F. ; Lugaresi, A. ; Izquierdo, G. ; Bergamaschi, R. ; Cabrera-Gomez, J.A. ; Pozzilli, C. ; Millefiorini, E. ; Alroughani, R. ; Boz, C. ; Pucci, E. ; Zimatore, G.B. ; Sola, P. ; Lus, G. ; Maimone, D. ; Avolio, C. ; Cocco, E. ; Sajedi, S.A. ; Costantino, G. ; Duquette, P. ; Shaygannejad, V. ; Petersen, T. ; Fernández Bolaños, R. ; Paolicelli, D. ; Tortorella, C. ; Spelman, T. ; Margari, L. ; Amato, M.P. ; Comi, G. ; Butzkueven, H. ; Trojano, M. ; Registry, on behalf of the Italian iMedWeb ; Registry, the MSBase ; Spitaleri, D. ; Rottoli, M.R. ; Ardito, B. ; Iuliano, G. ; Montanari, E. ; Granieri, E. ; Tedeschi, G. ; Bertolotto, A. ; Granella, F. ; Di Battista, G. ; Gallo, P. ; Cavalla, P. ; Bellantonio, P. ; De Robertis, F. ; Durelli, L. ; Scarpini, E. ; Rezzonico, M. ; Protti, A. ; Solaro, C. ; Corea, F. ; Bosco, A. ; Vianello, M. ; Ferrò, M.T. ; Balgera, R. ; Grasso, R. ; De Luca, G. ; Farina, D. ; Travaglini, D. ; di Ioia, M. ; Di Tommaso, V. ; Mancinelli, L. ; Pietrolongo, E. ; Hupperts, R. ; Rio, M.E. ; Terzi, M. ; Barnett, M. ; Slee, M. ; Van Pesch, V. ; Savino, A. ; Lechner-Scott, J. ; Grammond, P. ; Singhal, B. ; Zwanikken, C. ; Fiol, M. ; Patrucco, L. ; Paine, M. ; McCombefrom, P. ; Grand'Maison, F. / Prognostic indicators in pediatric clinically isolated syndrome. In: Annals of Neurology. 2017 ; Vol. 81, No. 5. pp. 729-739.

@article{ca92424880fb4536bc274fbfff7ae63a,

title = "Prognostic indicators in pediatric clinically isolated syndrome",

keywords = "azathioprine, beta interferon, glatiramer, immunomodulating agent, immunosuppressive agent, natalizumab, acute disseminated encephalomyelitis, adolescent, Article, brain stem, childhood disease, clinical assessment, clinical indicator, cohort analysis, controlled study, decision tree, demyelinating disease, disability, disease exacerbation, drug exposure, Expanded Disability Status Scale, female, follow up, hazard ratio, human, immunosuppressive treatment, major clinical study, male, multicenter study, multiple sclerosis, observational study, onset age, optic neuritis, pediatric onset multiple sclerosis, priority journal, prognosis, proportional hazards model, prospective study, recursive partitioning and amalgamation tree, regression analysis, relapse, risk factor, risk reduction, spinal cord disease, child, clinical trial, Demyelinating Diseases, diagnostic imaging, disease course, pathophysiology, register, retrospective study, Adolescent, Age of Onset, Child, Disease Progression, Female, Follow-Up Studies, Humans, Male, Multiple Sclerosis, Prognosis, Registries, Retrospective Studies, Risk Factors",

author = "P. Iaffaldano and M. Simone and G. Lucisano and A. Ghezzi and G. Coniglio and {Brescia Morra}, V. and G. Salemi and F. Patti and A. Lugaresi and G. Izquierdo and R. Bergamaschi and J.A. Cabrera-Gomez and C. Pozzilli and E. Millefiorini and R. Alroughani and C. Boz and E. Pucci and G.B. Zimatore and P. Sola and G. Lus and D. Maimone and C. Avolio and E. Cocco and S.A. Sajedi and G. Costantino and P. Duquette and V. Shaygannejad and T. Petersen and {Fern{\'a}ndez Bola{\~n}os}, R. and D. Paolicelli and C. Tortorella and T. Spelman and L. Margari and M.P. Amato and G. Comi and H. Butzkueven and M. Trojano and Registry, {on behalf of the Italian iMedWeb} and Registry, {the MSBase} and D. Spitaleri and M.R. Rottoli and B. Ardito and G. Iuliano and E. Montanari and E. Granieri and G. Tedeschi and A. Bertolotto and F. Granella and {Di Battista}, G. and P. Gallo and P. Cavalla and P. Bellantonio and {De Robertis}, F. and L. Durelli and E. Scarpini and M. Rezzonico and A. Protti and C. Solaro and F. Corea and A. Bosco and M. Vianello and M.T. Ferr{\`o} and R. Balgera and R. Grasso and {De Luca}, G. and D. Farina and D. Travaglini and {di Ioia}, M. and {Di Tommaso}, V. and L. Mancinelli and E. Pietrolongo and R. Hupperts and M.E. Rio and M. Terzi and M. Barnett and M. Slee and {Van Pesch}, V. and A. Savino and J. Lechner-Scott and P. Grammond and B. Singhal and C. Zwanikken and M. Fiol and L. Patrucco and M. Paine and P. McCombefrom and F. Grand'Maison",

year = "2017",

doi = "10.1002/ana.24938",

language = "English",

volume = "81",

pages = "729--739",

journal = "Annals of Neurology",

issn = "0364-5134",

publisher = "John Wiley and Sons Inc.",

number = "5",

}

TY - JOUR

T1 - Prognostic indicators in pediatric clinically isolated syndrome

AU - Iaffaldano, P.

AU - Simone, M.

AU - Lucisano, G.

AU - Ghezzi, A.

AU - Coniglio, G.

AU - Brescia Morra, V.

AU - Salemi, G.

AU - Patti, F.

AU - Lugaresi, A.

AU - Izquierdo, G.

AU - Bergamaschi, R.

AU - Cabrera-Gomez, J.A.

AU - Pozzilli, C.

AU - Millefiorini, E.

AU - Alroughani, R.

AU - Boz, C.

AU - Pucci, E.

AU - Zimatore, G.B.

AU - Sola, P.

AU - Lus, G.

AU - Maimone, D.

AU - Avolio, C.

AU - Cocco, E.

AU - Sajedi, S.A.

AU - Costantino, G.

AU - Duquette, P.

AU - Shaygannejad, V.

AU - Petersen, T.

AU - Fernández Bolaños, R.

AU - Paolicelli, D.

AU - Tortorella, C.

AU - Spelman, T.

AU - Margari, L.

AU - Amato, M.P.

AU - Comi, G.

AU - Butzkueven, H.

AU - Trojano, M.

AU - Registry, on behalf of the Italian iMedWeb

AU - Registry, the MSBase

AU - Spitaleri, D.

AU - Rottoli, M.R.

AU - Ardito, B.

AU - Iuliano, G.

AU - Montanari, E.

AU - Granieri, E.

AU - Tedeschi, G.

AU - Bertolotto, A.

AU - Granella, F.

AU - Di Battista, G.

AU - Gallo, P.

AU - Cavalla, P.

AU - Bellantonio, P.

AU - De Robertis, F.

AU - Durelli, L.

AU - Scarpini, E.

AU - Rezzonico, M.

AU - Protti, A.

AU - Solaro, C.

AU - Corea, F.

AU - Bosco, A.

AU - Vianello, M.

AU - Ferrò, M.T.

AU - Balgera, R.

AU - Grasso, R.

AU - De Luca, G.

AU - Farina, D.

AU - Travaglini, D.

AU - di Ioia, M.

AU - Di Tommaso, V.

AU - Mancinelli, L.

AU - Pietrolongo, E.

AU - Hupperts, R.

AU - Rio, M.E.

AU - Terzi, M.

AU - Barnett, M.

AU - Slee, M.

AU - Van Pesch, V.

AU - Savino, A.

AU - Lechner-Scott, J.

AU - Grammond, P.

AU - Singhal, B.

AU - Zwanikken, C.

AU - Fiol, M.

AU - Patrucco, L.

AU - Paine, M.

AU - McCombefrom, P.

AU - Grand'Maison, F.

PY - 2017

Y1 - 2017

KW - azathioprine

KW - beta interferon

KW - glatiramer

KW - immunomodulating agent

KW - immunosuppressive agent

KW - natalizumab, acute disseminated encephalomyelitis

KW - adolescent

KW - Article

KW - brain stem

KW - childhood disease

KW - clinical assessment

KW - clinical indicator

KW - cohort analysis

KW - controlled study

KW - decision tree

KW - demyelinating disease

KW - disability

KW - disease exacerbation

KW - drug exposure

KW - Expanded Disability Status Scale

KW - female

KW - follow up

KW - hazard ratio

KW - human

KW - immunosuppressive treatment

KW - major clinical study

KW - male

KW - multicenter study

KW - multiple sclerosis

KW - observational study

KW - onset age

KW - optic neuritis

KW - pediatric onset multiple sclerosis

KW - priority journal

KW - prognosis

KW - proportional hazards model

KW - prospective study

KW - recursive partitioning and amalgamation tree

KW - regression analysis

KW - relapse

KW - risk factor

KW - risk reduction

KW - spinal cord disease

KW - child

KW - clinical trial

KW - Demyelinating Diseases

KW - diagnostic imaging

KW - disease course

KW - pathophysiology

KW - register

KW - retrospective study, Adolescent

KW - Age of Onset

KW - Child

KW - Disease Progression

KW - Female

KW - Follow-Up Studies

KW - Humans

KW - Male

KW - Multiple Sclerosis

KW - Prognosis

KW - Registries

KW - Retrospective Studies

KW - Risk Factors

U2 - 10.1002/ana.24938

DO - 10.1002/ana.24938

M3 - Article

VL - 81

SP - 729

EP - 739

JO - Annals of Neurology

JF - Annals of Neurology

SN - 0364-5134

IS - 5

ER -