Prognostic parameters in metastatic spread of laryngeal cancer: clinico-histopathological correlations.

G. B. Galioto, E. Mevio, M. Benazzo, L. Arizzi, M. Scelsi

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Abstract

The authors present a series of 130 patients with laryngeal tumours submitted to total or horizontal laryngectomy and to neck dissection. The possible correlations between the staging and histology of the primary lesion, tumour marker (LASA) and the incidence of lymph node metastases are examined. The information provided by clinical and histopathological parameters is no doubt useful, but the margin of clinical error is high. On the contrary, the tumour marker concentration (LASA) was significantly higher in the patients whose lymph nodes were found to be histologically invaded, than in those without metastatic spread. Consequently, the LASA test may assume clinical importance before surgical therapy and in the follow-up of treated patients.

Original languageEnglish
Pages (from-to)303-308
Number of pages6
JournalClinical Otolaryngology and Allied Sciences
Volume12
Issue number4
Publication statusPublished - Aug 1987

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Laryngeal Neoplasms
Tumor Biomarkers
Lymph Nodes
Laryngectomy
Neck Dissection
Histology
Neoplasm Metastasis
Incidence
lipid-associated sialic acid
Neoplasms
Therapeutics

ASJC Scopus subject areas

  • Otorhinolaryngology

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Prognostic parameters in metastatic spread of laryngeal cancer : clinico-histopathological correlations. / Galioto, G. B.; Mevio, E.; Benazzo, M.; Arizzi, L.; Scelsi, M.

In: Clinical Otolaryngology and Allied Sciences, Vol. 12, No. 4, 08.1987, p. 303-308.

Research output: Contribution to journalArticle

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