Prognostic relevance of cathepsin D versus oestrogen receptors in node negative breast cancers

G. Granata, D. Coradini, V. Cappelleti, G. Di Fronzo

Research output: Contribution to journalArticle

Abstract

The concentration of total cathepsin D in cytosols of 199 node negative women with primary breast cancer in a 10-year retrospective cohort was assayed. Cathepsin D status alone was unable to predict disease-free or overall survival. However, those patients with receptor positive tumours who were cathepsin D positive had longer disease-free (P = 0.02) and overall survival (P = 0.01) than cathepsin D negative patients. Therefore, measurement of cathepsin D appears to provide additional prognostic information for the prediction of disease-free and overall survival in patients with node negative breast cancer.

Original languageEnglish
Pages (from-to)970-972
Number of pages3
JournalEuropean Journal of Cancer and Clinical Oncology
Volume27
Issue number8
DOIs
Publication statusPublished - 1991

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

Fingerprint Dive into the research topics of 'Prognostic relevance of cathepsin D versus oestrogen receptors in node negative breast cancers'. Together they form a unique fingerprint.

  • Cite this