Abstract
The concentration of total cathepsin D in cytosols of 199 node negative women with primary breast cancer in a 10-year retrospective cohort was assayed. Cathepsin D status alone was unable to predict disease-free or overall survival. However, those patients with receptor positive tumours who were cathepsin D positive had longer disease-free (P = 0.02) and overall survival (P = 0.01) than cathepsin D negative patients. Therefore, measurement of cathepsin D appears to provide additional prognostic information for the prediction of disease-free and overall survival in patients with node negative breast cancer.
| Original language | English |
|---|---|
| Pages (from-to) | 970-972 |
| Number of pages | 3 |
| Journal | European Journal of Cancer and Clinical Oncology |
| Volume | 27 |
| Issue number | 8 |
| DOIs | |
| Publication status | Published - 1991 |
ASJC Scopus subject areas
- Oncology
- Cancer Research
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Granata, G., Coradini, D., Cappelleti, V., & Di Fronzo, G. (1991). Prognostic relevance of cathepsin D versus oestrogen receptors in node negative breast cancers. European Journal of Cancer and Clinical Oncology, 27(8), 970-972. https://doi.org/10.1016/0277-5379(91)90260-K