Abstract
Fourteen cases of sarcomatoid carcinomas of breast were evaluated by means of a silver technique that selectively stains proteins located in the nucleolar organizer regions (Ag-NORs). The mean area of Ag-NORs (MNORA) was in each case quantitatively analyzed by means of an automated image analyzer. Patients who died early of the disease had a higher MNORA than patients who survived longer than 3 years. The difference was statistically significant. Ag-NORs might be a novel parameter of prognostic relevance in specific cases.
Original language | English |
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Pages (from-to) | 203-214 |
Number of pages | 12 |
Journal | Ultrastructural Pathology |
Volume | 15 |
Issue number | 3 |
DOIs | |
Publication status | Published - 1991 |
Keywords
- Breast
- Nucleolar organizer regions
- Prognosis
- Sarcomatoid carcinoma
ASJC Scopus subject areas
- Pathology and Forensic Medicine
- Structural Biology
- Instrumentation