Abstract
Fourteen cases of sarcomatoid carcinomas of breast were evaluated by means of a silver technique that selectively stains proteins located in the nucleolar organizer regions (Ag-NORs). The mean area of Ag-NORs (MNORA) was in each case quantitatively analyzed by means of an automated image analyzer. Patients who died early of the disease had a higher MNORA than patients who survived longer than 3 years. The difference was statistically significant. Ag-NORs might be a novel parameter of prognostic relevance in specific cases.
| Original language | English |
|---|---|
| Pages (from-to) | 203-214 |
| Number of pages | 12 |
| Journal | Ultrastructural Pathology |
| Volume | 15 |
| Issue number | 3 |
| DOIs | |
| Publication status | Published - 1991 |
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Keywords
- Breast
- Nucleolar organizer regions
- Prognosis
- Sarcomatoid carcinoma
ASJC Scopus subject areas
- Pathology and Forensic Medicine
- Structural Biology
- Instrumentation
Cite this
Prognostic relevance of silver-stained nucleolar proteins in sarcomatoid carcinomas of the breast. / Eusebi, Vincenzo; Cattani, Maria G.; Lamovec, Janez; Treré, Davide; Ceccarelli, Claudio; Veronesi, Paolo; Clemente, Claudio; Derenzini, Massimo.
In: Ultrastructural Pathology, Vol. 15, No. 3, 1991, p. 203-214.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Prognostic relevance of silver-stained nucleolar proteins in sarcomatoid carcinomas of the breast
AU - Eusebi, Vincenzo
AU - Cattani, Maria G.
AU - Lamovec, Janez
AU - Treré, Davide
AU - Ceccarelli, Claudio
AU - Veronesi, Paolo
AU - Clemente, Claudio
AU - Derenzini, Massimo
PY - 1991
Y1 - 1991
N2 - Fourteen cases of sarcomatoid carcinomas of breast were evaluated by means of a silver technique that selectively stains proteins located in the nucleolar organizer regions (Ag-NORs). The mean area of Ag-NORs (MNORA) was in each case quantitatively analyzed by means of an automated image analyzer. Patients who died early of the disease had a higher MNORA than patients who survived longer than 3 years. The difference was statistically significant. Ag-NORs might be a novel parameter of prognostic relevance in specific cases.
AB - Fourteen cases of sarcomatoid carcinomas of breast were evaluated by means of a silver technique that selectively stains proteins located in the nucleolar organizer regions (Ag-NORs). The mean area of Ag-NORs (MNORA) was in each case quantitatively analyzed by means of an automated image analyzer. Patients who died early of the disease had a higher MNORA than patients who survived longer than 3 years. The difference was statistically significant. Ag-NORs might be a novel parameter of prognostic relevance in specific cases.
KW - Breast
KW - Nucleolar organizer regions
KW - Prognosis
KW - Sarcomatoid carcinoma
UR - http://www.scopus.com/inward/record.url?scp=0025829147&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0025829147&partnerID=8YFLogxK
U2 - 10.3109/01913129109021882
DO - 10.3109/01913129109021882
M3 - Article
C2 - 1714652
AN - SCOPUS:0025829147
VL - 15
SP - 203
EP - 214
JO - Ultrastructural Pathology
JF - Ultrastructural Pathology
SN - 0191-3123
IS - 3
ER -