Prognostic relevance of silver-stained nucleolar proteins in sarcomatoid carcinomas of the breast

Vincenzo Eusebi; Maria G. Cattani; Janez Lamovec; Davide Treré; Claudio Ceccarelli; Paolo Veronesi; Claudio Clemente; Massimo Derenzini

doi:10.3109/01913129109021882

Prognostic relevance of silver-stained nucleolar proteins in sarcomatoid carcinomas of the breast

Vincenzo Eusebi, Maria G. Cattani, Janez Lamovec, Davide Treré, Claudio Ceccarelli, Paolo Veronesi, Claudio Clemente, Massimo Derenzini

Istituto Europeo di Oncologia

Research output: Contribution to journal › Article › peer-review

Abstract

Fourteen cases of sarcomatoid carcinomas of breast were evaluated by means of a silver technique that selectively stains proteins located in the nucleolar organizer regions (Ag-NORs). The mean area of Ag-NORs (MNORA) was in each case quantitatively analyzed by means of an automated image analyzer. Patients who died early of the disease had a higher MNORA than patients who survived longer than 3 years. The difference was statistically significant. Ag-NORs might be a novel parameter of prognostic relevance in specific cases.

Original language	English
Pages (from-to)	203-214
Number of pages	12
Journal	Ultrastructural Pathology
Volume	15
Issue number	3
DOIs	https://doi.org/10.3109/01913129109021882
Publication status	Published - 1991

Keywords

Breast
Nucleolar organizer regions
Prognosis
Sarcomatoid carcinoma

ASJC Scopus subject areas

Pathology and Forensic Medicine
Structural Biology
Instrumentation

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10.3109/01913129109021882

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Prognostic relevance of silver-stained nucleolar proteins in sarcomatoid carcinomas of the breast. / Eusebi, Vincenzo; Cattani, Maria G.; Lamovec, Janez; Treré, Davide; Ceccarelli, Claudio; Veronesi, Paolo; Clemente, Claudio; Derenzini, Massimo.

In: Ultrastructural Pathology, Vol. 15, No. 3, 1991, p. 203-214.

Research output: Contribution to journal › Article › peer-review

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abstract = "Fourteen cases of sarcomatoid carcinomas of breast were evaluated by means of a silver technique that selectively stains proteins located in the nucleolar organizer regions (Ag-NORs). The mean area of Ag-NORs (MNORA) was in each case quantitatively analyzed by means of an automated image analyzer. Patients who died early of the disease had a higher MNORA than patients who survived longer than 3 years. The difference was statistically significant. Ag-NORs might be a novel parameter of prognostic relevance in specific cases.",

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AU - Veronesi, Paolo

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